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Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Green tea component EGCG could potentially promote human hair growth.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride can cause sexual problems and depression in young men.

Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Finasteride helps protect brain in old male rats.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.

DHT affects testicular development and regulates spermatogenesis in some fish.

Post-finasteride syndrome's existence is uncertain; more research needed.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.