January 2024 in “Estetologia Medyczna i Kosmetologia” Most hair loss shampoos have unproven active ingredients.
April 2023 in “Journal of Investigative Dermatology” Cinchona succirubra extract with caffeine improves hair growth and reduces hair loss.
1 citations,
May 2021 in “Journal of Cosmetic Dermatology” Cosmetic foam product reduces hair loss and increases hair density in men.
2 citations,
July 2021 in “Dermatologic Therapy” A woman's hair loss after COVID-19 was likely due to a mix of pressure-induced alopecia and acute telogen effluvium.
67 citations,
November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
December 2022 in “Clinical and experimental dermatology and therapies” Adding the topical gel improved hair growth more than using minoxidil or finasteride alone.
January 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” Argan oil-based nano carriers could potentially deliver caffeine to hair follicles to treat hair loss.
3 citations,
January 2023 in “International Journal of Cosmetic Science” Coffee and its by-products are promising for skin health benefits in cosmetics and help reduce environmental impact.
1 citations,
July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
7 citations,
July 2018 in “International Journal of Applied Pharmaceutics” Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
8 citations,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
January 2020 in “Estetologia Medyczna i Kosmetologia” Most ingredients in anti-hair loss products lack scientific proof of effectiveness.
46 citations,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
The optimal concentration for caffeine release in gel form is 0.2% caffeine and 2.3% chitosan.
1 citations,
July 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” Topical caffeine improves hair loss intensity, speed, and shedding, and works better with minoxidil/azelaic acid.
1 citations,
March 2018 in “Dermatologie pro praxi” Most over-the-counter hair loss treatments lack strong evidence of effectiveness, except for minoxidil, which works but stops working if you stop using it.
January 2021 in “AIP conference proceedings” A hair serum made from coffee by-products can promote hair growth and is safe, but needs less stickiness.
3 citations,
January 2018 in “International Journal of Cosmetic Science” Hair stiffness increased by 13.2% after caffeine treatment, validating the Stiffness-Angle Law as an effective measurement method.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
November 2022 in “Journal of Investigative Dermatology” The document concludes that a new method has been developed to test anti-aging substances on human skin, showing that these substances can reduce skin aging signs.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.
September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
November 2024 in “International Journal of Molecular Sciences” Nanoparticles may improve caffeine delivery for hair growth, offering a potential alternative to minoxidil for hair loss treatment.
November 2023 in “Journal of Cosmetic Dermatology” The topical treatment with caffeine and Procapil 3% improved male pattern hair loss and was well tolerated after 12 weeks.
12 citations,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
2 citations,
January 2016 Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.
4 citations,
February 2022 in “Journal of Pharmaceutical and Biomedical Analysis” The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.
1 citations,
July 2023 in “Cosmetics” The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
August 2018 in “Jundishapur journal of natural pharmaceutical products” Transfollicular drug delivery can improve medication absorption through hair follicles.