UPLC-MS/MS Method for the Simultaneous Quantification of Caffeine and Illicit Psychoactive Drugs in Hair Using a Single-Step High-Speed Grinding Extraction – Insights into a Cut-Off Value for Caffeine Abuse

    February 2022 in “ Journal of Pharmaceutical and Biomedical Analysis ”
    Shan Jiang, Zhong Yuling, Hongwei Qiao … Mengxiang Su
    Studysummary The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.
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    Research cited in this study 2

    1. Caffeine Content in Newborn Hair Correlates with Maternal Dietary Intake European Journal of Nutrition · 2020
    2. The Measurement of Caffeine Concentration in Scalp Hair as an Indicator of Liver Function Journal of Pharmacy and Pharmacology · 1996