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Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Certain drugs change freshwater snail shells to a "banana" shape.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Too much androgen can cause hair loss; finasteride may help.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Treatment during development affects hormone balance and sexual behavior in male rats.