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Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.

Schisandra nigra extract may help hair grow by stimulating cells and preventing hair follicle damage.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Gene mutations can cause problems in male genital development.

Testosterone is crucial for development, growth, and various body functions in mammals.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Glioblastoma cells can make androgens, which might help the tumor grow.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.