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Two mouse mutations cause similar hair loss despite different skin changes.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Finasteride's two formulations absorb similarly, showing bioequivalence.

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

The research found that the gene activity in mouse skin stem cells changes significantly as they age.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Hair transplantation can effectively treat female pattern hair loss with the right patient selection and surgical skill.

Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

SCD-153 shows promise as an effective topical treatment for alopecia areata.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Minoxidil can increase hair density, speed up regrowth in transplanted hair, and slow down further hair loss, especially beneficial for women, young men with thinning hair, and those wanting to reconstruct the back of the scalp.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Immune cells are essential for early hair and skin development and healing.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Minoxidil and finasteride combined can effectively treat hair loss.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.