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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Researchers made two new compounds that could be used for medicine.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Combination therapy improves hair growth in advanced hair loss.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

New compounds may soon be tested to treat excessive hair growth in women.

Too much androgen can cause hair loss; finasteride may help.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.