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A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Phenylephrine may help prevent hair loss from pulling on the hair roots.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride may cause kidney damage.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Flutamide reduces hair growth better but has more side effects.

Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.

NAC1 controls certain enzymes that reduce root hair growth in Arabidopsis.

AR gene not major factor in female hair loss; different from male hair loss.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.