Search

everythinglearnresearchcommunity

for

Search:↓

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Too much androgen can cause hair loss; finasteride may help.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Finasteride doesn't affect sleep spindles in men.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

New genes and pathways are important for testosterone production and male sexual development.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

DHT, a testosterone byproduct, causes male pattern baldness.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.