Search

everythinglearnresearchcommunity

for

Search:↓

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Sebocytes play a key role in controlling androgen levels in human skin.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

A mix of sulforaphane, L-menthol, and dexpanthenol could help increase hair growth and reduce hair loss.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Testosterone is crucial for development, growth, and various body functions in mammals.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.