Search

everythinglearnresearchcommunity

for

Search:↓

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Finasteride blocks progesterone's effect on absence seizures in rats.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

The method effectively detects banned substances in urine for sports antidoping.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Compound 15a was effective in inhibiting 5α-reductase.