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Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Stem cells from hair follicles can safely treat hair loss.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Injecting a special gel with human protein particles can help hair grow.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Higher androgen levels do not cause baldness in men.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Watercress oil may promote hair growth by activating specific receptors.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.

Caragana korshinskii seed oil effectively treats fungal skin infections.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.