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New treatments for male hypogonadism are effective and should be personalized.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

PCOS is a long-term condition that needs more research for better understanding and treatment.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Ferulic acid may help control menstrual cycle-related epilepsy by affecting female hormones.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Testosterone helps human pancreatic cells increase insulin release.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Eating nuts, chocolate candy, and red tea might worsen acne, while eating more fresh vegetables could reduce it.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Early NAS level changes affect alcohol consumption vulnerability.