research Case 1: Clitoromegaly, Oligomenorrhea, and Hirsutism in a 17-Year-Old Transgender Male
Parental support and gender-affirming care are crucial for the mental health of transgender adolescents.
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research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services
GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.
research Network Pharmacology Reveals Curcuma Aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia
Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.
research Investigation of the Role of SIRT3, SIRT7, NFATC1, and PDL-1 Genes in Androgenetic Alopecia
SIRT3 and SIRT7 decrease, while NFATC1 and PDL-1 increase in Androgenetic Alopecia.
research Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia
β1 integrin may indicate and influence the severity of hair loss in androgenetic alopecia.
research GLP-1 Agonists and Hair Loss: A Call for Further Investigation
More research is needed to understand if GLP-1 agonists affect hair health.
research A Patient With Insulin-Dependent Diabetes Mellitus 1 Year After Being Diagnosed With Membranous Glomerulonephritis
A 9-year-old girl developed type 1 diabetes and alopecia after being treated for a rare kidney disease.
research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.
research Autoimmune Disorders Associated with Type 1 Diabetes: Clinical Overview and Principles of Management
Type 1 diabetes patients often have other autoimmune diseases, which complicate their care.
research Evaluation of Paraoxonase 1 Serum Level in Male Androgenetic Alopecia Patients
Men with male pattern baldness have lower levels of the antioxidant PON1.
research Identification of an Osteopontin-Derived Peptide That Binds Neuropilin-1 and Activates Vascular Cells
FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
research Risk of Merkel Cell Carcinoma Progression After Treatment Discontinuation in Patients With an Objective Response to Anti-PD-(L)1 Immunotherapy
Longer immunotherapy treatment may improve outcomes for Merkel cell carcinoma patients.
research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research Effects of Different Concentrations of Androgens on KAP24.1 Gene Expression in Hetian Sheep and Karakul Sheep
Different androgen concentrations affect wool-related gene expression differently in Hetian and Karakul sheep breeds.
research Spatiotemporal Dynamics of Sensory Neuron and Merkel-Cell Remodeling During Epidermal Homeostasis
Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
research Gremlin-1 Level in Polycystic Ovary Syndrome and Its Clinical Correlations: A Case Control Study
People with polycystic ovary syndrome have higher levels of Gremlin-1.
research Deregulation of Toll Like Receptor Signaling and Association With Caveolin-1 in Lichen Planopilaris Reveals a Novel Mechanism in Pathogenesis of Scarring Alopecia
The study suggests that changes in immune system receptors and their interaction with a cell component may be important in the development of a type of hair loss condition.
research Expression of Programmed Cell Death 1 Inversely Correlated With the Density of CD8+ T Cells Infiltrating Hair Follicles in Alopecia Areata
Higher PD-1 levels are linked to fewer immune cells in hair follicles in alopecia areata.
research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research Medications Affecting the Insulin-Like Growth Factor 1/Growth Hormone Axis, Including Teprotumumab, Somatostatin Analogs, and Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies, Are Associated With Elevated Reporting Odds of Alopecia in Women: A Pharmacovigilance Study
Some drugs linked to growth hormones may increase the chance of hair loss in women.
research Metformin Effects on Blood Levels of Gremlin-1 in Polycystic Ovarian Women
Metformin lowers gremlin-1 and improves insulin resistance in women with PCOS.
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
research A Rare Association of Mauriac Syndrome and Van Wyk-Grumbach Syndrome in a Young Saudi Girl with Poorly Controlled Type 1 Diabetes and Hypothyroidism: A Case Report and Brief Literature Review
A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.
research KRT17 Promotes Endometrial Cancer Cell Migration and Angiogenesis by Regulating HIF-1α/VEGF Pathway
KRT17 may be a new target for endometrial cancer treatment because it helps cancer cells move and form new blood vessels.
research Defective Expression of the Gap Junction Protein Pannexin-1 Channel Contributes to the Formation of PCOS-Related Androgenetic Alopecia
Higher levels of the protein Pannexin-1 may play a role in hair loss in women with PCOS.
research Exploring the Effects of Wetting and Free Fatty Acid Deposition on a Hair Fiber Surface Model Incorporating Keratin Associated Protein 5-1
Water and fatty acids affect hair's surface differently based on hair damage, and models can help understand hair-cosmetic interactions.
research Evaluation of Serum Level of Human Beta Defensin 1 in Patients With Alopecia Areata
Human Beta Defensin 1 levels do not predict the risk or severity of Alopecia Areata.
research Serum Dickkopf-1 Level in Patients of Cicatricial and Non-Cicatricial Alopecia
People with non-scarring hair loss have higher levels of DKK-1, a protein linked to hair growth, than those with scarring hair loss or no hair loss.
research Estimation of Serum Level of Omentin-1 in Hirsute Females: A Single Center Study
Females with idiopathic hirsutism have higher levels of omentin-1, which may lead to excessive hair growth.