The hair follicle enigma
May 2017
in “Experimental Dermatology”
TLDR The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
The document "The Hair Follicle Enigma" by Dr. Bruno Bernard from May 9, 2017, addresses the complexities of hair follicle biology and the gaps in understanding its signaling pathways and their effects on hair conditions such as thinning, whitening, and alopecia. It suggests that future research could benefit from computational approaches and acknowledges the limitations of current hair treatment products. The review also discusses the importance of proteoglycans, lipids, and exosomes in hair follicle structure and function, and the need for an integrative approach to fully understand the hair follicle. Additionally, it examines the roles of keratins, melanocyte distribution, stem cell functionality, and the regulation of hair growth phases, highlighting the involvement of glycans and related enzymes in key signaling pathways that affect hair follicle behavior.
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