The Challenging Role of Antiandrogens in the Management of Polycystic Ovary Syndrome

    November 2021 in “ Elsevier eBooks ”
    Kasiani Papadimitriou, Panagiotis Anagnostis, Dimitrios G. Goulis
    Studysummary This review discusses antiandrogen therapy for polycystic ovary syndrome, focusing on strategies to manage excessive androgen secretion, but it reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 29

    1. Fundamental Concepts and Novel Aspects of Polycystic Ovarian Syndrome: Expert Consensus Resolutions Frontiers in Endocrinology · 2020
    2. The Efficacy and Use of Finasteride in Women: A Systematic Review International Journal of Dermatology · 2019
    3. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    4. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    5. Treatment Options for Hirsutism: A Systematic Review and Network Meta-Analysis The Journal of Clinical Endocrinology & Metabolism · 2018
    6. Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial The Journal of Clinical Endocrinology & Metabolism · 2017
    7. Presentation of a Meningioma in a Transwoman After Nine Years of Cyproterone Acetate and Estradiol Intake: Case Report and Literature Review Gynecological Endocrinology · 2017
    8. The Use of Cyproterone Acetate/Ethinyl Estradiol in Hyperandrogenic Skin Symptoms: A Review The European Journal of Contraception & Reproductive Health Care · 2017
    9. Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review American Journal of Clinical Dermatology · 2017
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    17. Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study Journal of Pediatric and Adolescent Gynecology · 2014
    18. Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline The Journal of Clinical Endocrinology and Metabolism · 2013
    19. Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study The Journal of Clinical Endocrinology and Metabolism · 2013
    20. Hepatotoxicity with Low- and Ultralow-Dose Flutamide: A Surveillance Study on 203 Hyperandrogenic Young Females Fertility and Sterility · 2012
    21. Effectiveness of Ethinylestradiol/Chlormadinone Acetate in Treating Dermatological Conditions Related to High Androgen Levels American Journal of Clinical Dermatology · 2011
    22. Anti-Androgen Treatments for Hirsutism and Acne in Women of Childbearing Age Annales d'endocrinologie · 2010
    23. Lack of Effect of a Spironolactone-Containing Cream on Hair Growth in Hirsute Women Dermatology · 2009
    24. Effect of Finasteride on Ovulation Induction in Nonresponder (Hyperandrogenic) Polycystic Ovary Syndrome (PCOS) Women Fertility and Sterility · 2009
    25. Profile of the Progesterone Derivative Chlormadinone Acetate: Pharmacodynamic Properties and Therapeutic Applications Contraception · 2009
    26. Pharmacology of Different Progestogens: The Special Case of Drospirenone Climacteric · 2005
    27. Intermittent Low-Dose Finasteride Is as Effective as Daily Administration for the Treatment of Hirsute Women Fertility and Sterility · 2004
    28. Progestogens With Antiandrogenic Properties Drugs · 2003
    29. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996

    Related research 7

    1. The Challenging Role of Antiandrogens in the Management of Polycystic Ovary Syndrome Elsevier eBooks · 2021
    2. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    3. Pharmacological Options for Treatment of Hyperandrogenic Disorders Mini-reviews in Medicinal Chemistry · 2009
    4. Anti-Androgens for the Treatment of Hirsutism Expert opinion on investigational drugs · 2002
    5. Current Aspects of Antiandrogen Therapy in Women Current Pharmaceutical Design · 1999
    6. Other Antiandrogens: Alternative Treatments for Acne and Hirsutism Dermatology · 1998
    7. Treatment of Hyperandrogenism in Women Gynecological Endocrinology · 1996