Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling

    December 2022 in “ npj Regenerative Medicine ”
    Charlie Colin-Pierre, Oussama El Baraka, Louis Danoux … Stéphane Brezillon
    Studysummary This review discusses the role of heparan sulfate proteoglycans in regulating stem cell fate and highlights their potential as targets for addressing hair loss, without reporting new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 31

    1. The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis Frontiers in cell and developmental biology · 2021
    2. Hair Histology and Glycosaminoglycans Distribution Probed by Infrared Spectral Imaging: Focus on Heparan Sulfate Proteoglycan and Glypican-1 During Hair Growth Cycle Biomolecules · 2021
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    17. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011
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    20. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
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    Related research 2

    1. Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling npj Regenerative Medicine · 2022
    2. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010