Efficacy of Human Foreskin Fibroblast-Conditioned Medium in the Treatment of Androgenic Alopecia: A Pilot Trial

    January 2026 in “ Dermatologic Therapy ”
    E. Behrangi, N SAMANI, Ehsan Taghiabadi … Mohammad Ali Nilforoushzadeh
    Studysummary This study found that treatment with human foreskin fibroblast conditioned medium improved both objective measures like hair density and subjective satisfaction in patients with androgenetic alopecia.
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    Research cited in this study 12

    1. Regenerative Medicine in the Treatment of Specific Dermatologic Disorders: A Systematic Review of Randomized Controlled Clinical Trials Stem cell research & therapy · 2024
    2. Autologous Adipose Tissue Injection in the Treatment of Alopecia: A Mini-Review Journal of Cosmetic Dermatology · 2023
    3. Stem Cell-Derived Conditioned Medium for Alopecia: A Systematic Review and Meta-Analysis Journal of plastic, reconstructive & aesthetic surgery · 2023
    4. Combination of Adipose-Derived Stem Cell Conditioned Media and Minoxidil for Hair Regrowth in Male Androgenetic Alopecia: A Randomized, Double-Blind Clinical Trial Stem Cell Research & Therapy · 2023
    5. Proteomic Identification and Quantification of Secretory Proteins in Human Dermal Fibroblast-Conditioned Medium for Wound Repair and Hair Regeneration Clinical, Cosmetic and Investigational Dermatology · 2023
    6. Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review Cells · 2023
    7. Promotion of Hair Growth by Conditioned Medium from Extracellular Matrix/Stromal Vascular Fraction Gel in C57BL/6 Mice Stem Cells International · 2020
    8. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth Cells · 2020
    9. Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium Dermatologic Surgery · 2019
    10. Androgenetic Alopecia: A Review Endocrine · 2017
    11. Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study International Journal of Dermatology · 2015
    12. Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth Scientific Reports · 2014