Proteomic Identification and Quantification of Secretory Proteins in Human Dermal Fibroblast-Conditioned Medium for Wound Repair and Hair Regeneration
May 2023
in “
Clinical, Cosmetic and Investigational Dermatology
”
TLDR The research found proteins in human skin cells that help with wound healing and hair growth, which could lead to new treatments.
The study identified 337 secretory proteins from human dermal fibroblasts using Dermal Fibroblast-Conditioned Medium (DFCM). Of these, 160 proteins were potentially involved in wound repair and 57 were associated with hair regeneration. These proteins were further analyzed and classified into different networks. The study concluded that these DFCM proteins are involved in various pathways that promote wound repair and hair regeneration, suggesting a potential avenue for therapeutic development. However, the specific role of each DFCM protein in these processes requires further investigation.
