New Modalities in the Treatment of Refractory Alopecia Areata

    May 2017 in “ InTech eBooks ”
    Arzu Kılıç
    Studysummary This review summarizes current treatments for recalcitrant alopecia areata and recent therapeutic developments targeting specific immunological pathways, reporting no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 57

    1. Intramuscular Triamcinolone Acetonide: An Undervalued Option for Refractory Alopecia Areata Journal of dermatology · 2016
    2. Efficacy of Tofacitinib in Treatment of Alopecia Universalis in Two Patients Journal of the European Academy of Dermatology and Venereology · 2016
    3. A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata Expert Opinion on Biological Therapy · 2016
    4. Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers Experimental Dermatology · 2016
    5. Transient Efficacy of Tofacitinib in Alopecia Areata Universalis Case Reports in Dermatology · 2016
    6. Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata Dermatology · 2016
    7. Biomarkers of Alopecia Areata Disease Activity and Response to Corticosteroid Treatment Experimental dermatology · 2015
    8. Extensive Alopecia Areata Is Reversed by IL-12/IL-23p40 Cytokine Antagonism The Journal of Allergy and Clinical Immunology · 2015
    9. Successful Treatment of Corticosteroid-Resistant Ophiasis-Type Alopecia Areata with Platelet-Rich Plasma JAAD case reports · 2015
    10. Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2015
    11. Imbalance of T-Helper 17 and Regulatory T Cells in Patients with Alopecia Areata The Journal of Dermatology · 2015
    12. Contact Immunotherapy-Resistant Alopecia Areata Totalis/Universalis Reactive to Topical Corticosteroid The Journal of Dermatology · 2015
    13. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015
    14. Efficacy and Safety of Diphenylcyclopropenone Alone or in Combination with Anthralin in the Treatment of Chronic Extensive Alopecia Areata: A Retrospective Case Series Journal of the American Academy of Dermatology · 2015
    15. The Genetics Of Alopecia Areata: New Approaches, New Findings, New Treatments Journal of Dermatological Science · 2015
    16. Alopecia Areata: Overview and Treatment Options Current problems in dermatology · 2015
    17. Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience Indian Journal of Plastic Surgery · 2015
    18. Treatment of Alopecia Areata with Squaric Acid Dibutylester Clinics in dermatology · 2014
    19. The PDE4 Inhibitor, Apremilast, Suppresses Experimentally Induced Alopecia Areata in Human Skin In Vivo Journal of Dermatological Science · 2014
    20. Alopecia Universalis Successfully Treated With Adalimumab JAMA dermatology · 2014
    21. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    22. Alopecia Areata: An Evidence-Based Treatment Update American journal of clinical dermatology · 2014
    23. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014
    24. How Effective Is Intralesional Injection of Triamcinolone Acetonide Compared with Topical Treatments in Inducing and Maintaining Hair Growth in Patients with Alopecia Areata? A Critically Appraised Topic British journal of dermatology/British journal of dermatology, Supplement · 2014
    25. Current Treatment of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    26. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    27. The Effect of Oral Cyclosporine in the Treatment of Severe Alopecia Areata Cutaneous and ocular toxicology · 2013
    28. A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata British Journal of Dermatology · 2013
    29. Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata Clinical and Developmental Immunology · 2013
    30. Combination Therapy with Cyclosporine and Psoralen Plus Ultraviolet A in Patients with Severe Alopecia Areata: A Retrospective Study with a Self-Controlled Design Annals of dermatology/Annals of Dermatology · 2013
    31. Alopecia Areata Update Dermatologic Clinics · 2012
    32. British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012 British Journal of Dermatology · 2012
    33. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    34. Interest of High-Dose Pulse Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata: A Retrospective Case Series Dermatology · 2012
    35. Comparison of Treatment with Clobetasol Propionate 0.05% and Topical Pimecrolimus 1% in Alopecia Areata Journal of Dermatological Treatment · 2011
    36. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    37. Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions Journal of Dermatological Science · 2010
    38. Alopecia Areata as Another Immune-Mediated Disease Developed in Patients Treated with Tumor Necrosis Factor-Alpha Blocker Agents Journal of the European Academy of Dermatology and Venereology · 2010
    39. Diphencyprone and Topical Tacrolimus as Two Topical Immunotherapeutic Modalities: Are They Effective in the Treatment of Alopecia Areata Among Egyptian Patients? A Study Using CD4, CD8, and MHC II as Markers Journal of dermatological treatment · 2010
    40. Alopecia Areata Update Journal of the American Academy of Dermatology · 2010
    41. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    42. Latanoprost in the Treatment of Eyelash Alopecia in Alopecia Areata Universalis Journal of The European Academy of Dermatology and Venereology · 2009
    43. Phase I/II Randomized Bilateral Half-Head Comparison of Topical Bexarotene 1% Gel for Alopecia Areata Journal of the American Academy of Dermatology · 2009
    44. 308-nm Excimer Laser for the Treatment of Alopecia Areata in Children Pediatric dermatology · 2009
    45. Letter Dermatologic surgery · 2009
    46. Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata Journal of The American Academy of Dermatology · 2009
    47. Treatment of Persistent Alopecia Areata with Sulfasalazine International Journal of Dermatology · 2008
    48. Interventions for Alopecia Areata Cochrane library · 2008
    49. Lack of Response of Alopecia Areata to Pimecrolimus Cream Clinical and experimental dermatology · 2007
    50. Alopecia Areata: Overview and Treatment Options International Journal of Dermatology · 2007
    51. Development of Alopecia Areata Universalis in a Patient Receiving Adalimumab Archives of dermatology · 2006
    52. Use of the Pulsed Infrared Diode Laser (904 nm) in the Treatment of Alopecia Areata Journal of cosmetic and laser therapy · 2006
    53. Lack of Efficacy of Topical Latanoprost in the Treatment of Eyebrow Alopecia Areata Journal of The American Academy of Dermatology · 2005
    54. Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle Autoimmunity Reviews · 2005
    55. 308-Nm Excimer Laser Therapy in Alopecia Areata Journal of the American Academy of Dermatology · 2004
    56. PUVA Treatment of Alopecia Areata Partialis, Totalis, and Universalis: Audit of 10 Years' Experience at St John's Institute of Dermatology British journal of dermatology/British journal of dermatology, Supplement · 1995
    57. Evaluation of Anthralin in the Treatment of Alopecia Areata Archives of dermatology · 1987

    Related research 4

    1. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    2. Topical and Intralesional Therapies for Alopecia Areata Dermatologic therapy · 2011
    3. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    4. Adverse Systemic Reaction to Dinitrochlorobenzene Archives of Dermatology · 1982