Intramuscular Triamcinolone Acetonide: An Undervalued Option for Refractory Alopecia Areata

July 2016 in “ Journal of dermatology ”

Jeong Taeg Seo, Young In Lee, Sang Min Hwang, Zhenlong Zheng, Doyoung Kim

triamcinolone acetonide intramuscular triamcinolone acetonide alopecia areata hair regrowth dysmenorrhea osteoporosis TAC AA

TLDR Intramuscular triamcinolone acetonide is an effective treatment for severe alopecia areata, especially in males.

The study evaluated the efficacy and safety of intramuscular triamcinolone acetonide (i.m. TAC) as a rescue therapy for refractory alopecia areata (AA) in 27 patients. The treatment showed a 63% response rate, with all patients exhibiting inactive disease post-treatment. Hair regrowth was inversely related to initial scalp involvement. Adverse effects were limited to female patients, including dysmenorrhea and osteoporosis. The study concluded that i.m. TAC could be a valuable option for managing active hair loss and promoting hair regrowth in refractory AA, particularly in male patients.

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