Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

    October 2022 in “ Research Square (Research Square) ”
    Xiaogao Diao, Lingyun Yao, Tao Duan … Wei Zhang

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that melatonin treatment in Cashmere goat kids enhances the density of secondary hair follicles and improves Cashmere quality by regulating the MAPK pathway and reducing cell apoptosis.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

    1. Vitamin A Alleviates Heat Stress-Induced Damage to Hair Follicle Development in Rex Rabbits Journal of the Science of Food and Agriculture · 2021
    2. DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages Stem cell research & therapy · 2020
    3. Melatonin Supplement Induced Hair Follicle Development in Offspring Rex Rabbits Journal of Animal Physiology and Animal Nutrition · 2020
    4. Effect of Nutritional Restriction on the Hair Follicles Development and Skin Transcriptome of Chinese Merino Sheep Animals · 2020
    5. Screening the Key Genes of Hair Follicle Growth Cycle in Inner Mongolian Cashmere Goat Based on RNA Sequencing Archiv für Tierzucht · 2020
    6. The Functions of Ocu-miR-205 in Regulating Hair Follicle Development in Rex Rabbits BMC Developmental Biology · 2020
    7. Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit Hair Follicle Cycle by RNA Sequencing Frontiers in genetics · 2019
    8. Melatonin Promotes Secondary Hair Follicle Development in Early Postnatal Cashmere Goats and Improves Cashmere Quantity and Quality by Enhancing Antioxidant Capacity and Suppressing Apoptosis Journal of Pineal Research · 2019
    9. Comparative Study on Seasonal Hair Follicle Cycling by Analysis of the Transcriptomes from Cashmere and Milk Goats Genomics · 2019
    10. Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling Molecular therapy · 2017
    11. Expression of Fox-Related Genes in the Skin Follicles of Inner Mongolia Cashmere Goat Asian-Australasian journal of animal sciences · 2017
    12. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated With Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016
    13. Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss American Journal of Clinical Dermatology · 2016
    14. The Circadian Clock in Skin Journal of Biological Rhythms · 2015
    15. Melatonin and the Hair Follicle Journal of pineal research · 2007
    16. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    17. Seasonal Fiber Growth Cycles of Ferrets (Mustela Putorius Furo) and Long-Term Effects of Melatonin Treatment ˜The œjournal of experimental zoology/Journal of experimental zoology · 1995
    18. Melatonin and Fleece Growth in Australian Cashmere Goats Small ruminant research · 1995
    19. Effect of Immunization Against Melatonin on Seasonal Fleece Growth in Feral Goats Journal of pineal research · 1992

    Related research 6

    1. Single-Cell Sequencing Reveals the New Existence Form of Dermal Papilla Cells in the Hair Follicle Regeneration of Cashmere Goats Genomics · 2022
    2. Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape BMC genomics · 2020
    3. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Hair Follicle Cycling in Cashmere Goats Research Square (Research Square) · 2019
    4. Hair Follicle Transcriptome Profiles During the Transition from Anagen to Catagen in Cashmere Goat (Capra Hircus) Genetics and molecular research · 2015
    5. Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling PloS one · 2013
    6. Hoxc13/β-Catenin Correlation with Hair Follicle Activity in Cashmere Goat Journal of integrative agriculture/Journal of Integrative Agriculture · 2012