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Did you mean miR-21?

Glossary miR-21

small RNA molecule regulating gene expression and hair follicle development

miR-21 is a type of microRNA, which are small molecules that help regulate gene expression in cells. It is known to play a role in various biological processes, including cell growth, apoptosis (programmed cell death), and differentiation. In the context of hair and alopecia, miR-21 has been implicated in the regulation of hair follicle development and cycling, and its dysregulation may contribute to hair loss conditions.

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Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

research Melatonin regulates the mitogen-activated protein kinase ( MAPK ) pathway via the circMPP5-miR-211-MAPK3 axis to induce secondary hair follicle differentiation and development in newborn Cashmere goat kids

1 citations , October 2022 in “Research Square (Research Square)”

This study found that melatonin treatment in Cashmere goat kids enhances the density of secondary hair follicles and improves Cashmere quality by regulating the MAPK pathway and reducing cell apoptosis.

research MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development

4 citations , March 2024 in “Cells”

This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.

Melatonin Promotes the Development of Secondary Hair Follicles by Regulating circMPP5

research Melatonin promotes the development of the secondary hair follicles by regulating circMPP5

1 citations , April 2023 in “Journal of Animal Science and Biotechnology”

This study found that treating cashmere goat kids with melatonin significantly increased secondary hair follicle density, improving cashmere quality and yield, likely through mechanisms involving the MAPK signaling pathway.

research Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling

65 citations , July 2020 in “Science Advances”

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

research The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat

13 citations , September 2018 in “Scientific Reports”

In this study, researchers found that microRNAs and specific target genes, such as MiR-195 and genes like CHP1, SMAD2, FZD6, and SIAH1, play significant roles in regulating hair follicle initiation in cashmere goats.

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Related Terms

Research

research Melatonin regulates the mitogen-activated protein kinase ( MAPK ) pathway via the circMPP5-miR-211-MAPK3 axis to induce secondary hair follicle differentiation and development in newborn Cashmere goat kids

research MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development

research Melatonin promotes the development of the secondary hair follicles by regulating circMPP5

research Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling

research The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat

Experts

Dr. Mir Malkani, MBBS, FRCS

Dr. Mir Shahnawaz, MD, MBBS

Dr. Joan Mir, MD

Dr. Shuaib Mir, MD

Dr. Marc Mir, MD

Dr. Mubashar Mashqoor Mir, MD, DNB, MNAMS, FHR

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