Exploiting the Keratin 17 Gene Promoter to Visualize Live Cells in Epithelial Appendages of Mice

July 2005 in “ Molecular and Cellular Biology ”

Nicholas Bianchi, Daryle J. DePianto, Kevin McGowan, Changhong Gu, Pierre A. Coulombe

keratin 17 green fluorescent protein GFP hair follicles hairless mutation sonic hedgehog signaling K17 regulation epithelial appendages

Studysummary This study showed that a 2-kilobase upstream region of the mouse keratin 17 gene enables targeted GFP expression in major epithelial appendages of transgenic mice, indicating sonic hedgehog's involvement in its regulation.

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