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GlossaryHedgehog signaling pathway

regulates cell growth and development through protein-receptor interactions

The Hedgehog signaling pathway is a crucial mechanism in developmental biology that regulates cell growth, differentiation, and tissue patterning. It involves the Hedgehog proteins binding to receptors on cell surfaces, which then trigger a cascade of intracellular events that influence gene expression. This pathway is essential for proper embryonic development and, when dysregulated, can lead to conditions such as cancer and congenital disorders.

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research Polycomb-Mediated Repression and Sonic Hedgehog Signaling Regulate Merkel Cell Specification

April 2016 in “Journal of Investigative Dermatology”

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

14 citations , June 2018 in “Frontiers in pharmacology”

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

research Author Response: Lhx2 as a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis

October 2022

Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.

research Editor's Evaluation: Lhx2 Is a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis

April 2022

Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.

research Decision Letter: Lhx2 Is a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis

April 2022

Lhx2 helps retinal cells respond to signals for eye development.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Maybe oral min was not that good of an idea for someone this naturally hairy

in Satire 413 upvotes 2 years ago

User discusses increased body hair after using oral minoxidil for hair loss treatment. Others share experiences and debate benefits of being hairy versus bald.

community Hair gel makes my hair look terribly unhealthy?!

in Styling 267 upvotes 7 months ago

Avoid hair gel; use sea salt spray, matte clay, or styling powder for volume. Use finasteride and minoxidil for hair loss.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 1 year ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community Stemson Therapeutics Announces Technological Breakthrough in new Hair Growth

in Research/Science 62 upvotes 1 year ago

Stemson Therapeutics announced a breakthrough in hair growth technology using stem cells. Users discussed the potential high cost and skepticism about the treatment's accessibility.

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