Heat-Treated Limosilactobacillus Fermentum LM1020 with Menthol, Salicylic Acid, and Panthenol Promotes Hair Growth and Regulates Scalp Microbiome Balance in Androgenetic Alopecia: A Double-Blind, Randomized, and Placebo-Controlled Clinical Trial

    Won‐Young Bae, Woo‐Hyun Jung, So Lim Shin … Ju Hee Lee
    Studysummary This study investigated the effects of heat-treated Limosilactobacillus fermentum LM1020 on hair growth and reported increased hair density, improved cellular activity, and beneficial scalp microbiota changes in patients with androgenetic alopecia over 24 weeks.
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    Research cited in this study 14

    1. Heat-Killed Lacticaseibacillus Paracasei GMNL-653 Ameliorates Human Scalp Health by Regulating Scalp Microbiome BMC Microbiology · 2023
    2. Laser Capture Microdissection as a Method for Investigating the Human Hair Follicle Microbiome Reveals Region-Specific Differences in the Bacteriome Profile BMC Research Notes · 2023
    3. A Potential Predictive Role of the Scalp Microbiome Profiling in Patients with Alopecia Areata: Staphylococcus Caprae, Corynebacterium, and Cutibacterium Species Microorganisms · 2022
    4. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    5. Scalp Microbiome and Sebum Composition in Japanese Male Individuals with and without Androgenetic Alopecia Microorganisms · 2021
    6. Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells Current Issues in Molecular Biology · 2021
    7. Lactobacillus Paracasei HY7015 Promotes Hair Growth in a Telogenic Mouse Model Journal of Medicinal Food · 2021
    8. Sulforaphane, L-Menthol, and Dexpanthenol as a Novel Active Cosmetic Ingredient Composition for Relieving Hair Loss Symptoms Cosmetics · 2021
    9. Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2020
    10. Autologous Activated Platelet-Rich Plasma in Hair Growth: A Pilot Study in Male Androgenetic Alopecia with In Vitro Bioactivity Investigation Journal of Cosmetic Dermatology · 2020
    11. Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens Dermatologic Therapy · 2019
    12. Investigation on Microecology of Hair Root Fungi in Androgenetic Alopecia Patients Mycopathologia · 2019
    13. Microbiome in the Hair Follicle of Androgenetic Alopecia Patients PLOS ONE · 2019
    14. An Overview of Herbal Alternatives in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019

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