Assessment of Efficacy and Safety Profile of Platelet-Rich Plasma Therapy with Dermaroller in the Treatment of Female Pattern Hair Loss

May 2020

B. Prithivirajan

Platelet Rich Plasma PRP Derma roller female pattern hair loss hair re-growth hair fall

TLDR PRP therapy with Derma roller effectively promotes hair re-growth and reduces hair fall in women with pattern hair loss.

In 2020, a study was conducted on 40 patients diagnosed with female pattern hair loss to assess the efficacy and safety of Platelet Rich Plasma (PRP) therapy with Derma roller. The patients underwent four sessions of PRP with Derma roller at 1-month intervals. The results showed that 87% of patients saw an improvement in the grade of hair loss after 6 months, with significant improvement observed after three sessions. The mean quality of life of the patients improved from 11 to 8, indicating a shift from a very large to a moderate effect on the patient's life. The study concluded that PRP therapy with Derma roller can be considered a viable treatment option for female pattern hair loss due to its good safety profile and effectiveness in promoting hair re-growth and reducing hair fall.

View this study on repository-tnmgrmu.ac.in →

Discuss this study in the Community →

Cited in this study

37 / 37 results

research Genetic and Molecular Aspects of Androgenetic Alopecia

24 citations , May 2018 in “Indian Journal of Dermatology, Venereology and Leprology”

research The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

52 citations , February 2018 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density and thickness in women with hair loss.

research A Comparative Study of Treatment Modalities in Female Androgenetic Alopecia

3 citations , December 2016 in “International Journal of Research in Medical Sciences”

Using both minoxidil and platelet-rich plasma therapy together is more effective for hair growth in women than using minoxidil alone.

research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia

60 citations , December 2016 in “Dermatologic Surgery”

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations , October 2014 in “Journal of Cutaneous and Aesthetic Surgery”

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

research Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia

35 citations , June 2014 in “British Journal of Dermatology”

Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.

research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration

170 citations , January 2013 in “Journal of Investigative Dermatology”

Wnt ligands are crucial for hair growth and repair.

research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments

58 citations , January 2013 in “Dermatologic Clinics”

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

research Reliability of the Pattern Hair Loss Classifications: A Comparison of the Basic and Specific and Norwood–Hamilton Classifications

16 citations , October 2012 in “The Journal of Dermatology”

The BASP classification is more reliable than the Norwood-Hamilton for classifying hair loss in men and women.

research Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth

22 citations , July 2012 in “International Journal of Trichology”

Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , July 2012 in “Dermatologic Surgery”

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

research Investigation of the Male Pattern Baldness Major Genetic Susceptibility Loci AR/EDA2R and 20p11 in Female Pattern Hair Loss

38 citations , June 2012 in “British Journal of Dermatology”

AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.

research The Human Hair Follicle, A Bistable Organ?

45 citations , March 2012 in “Experimental Dermatology”

Human hair follicles switch between active and resting phases unpredictably.

research Alopecia: A Review of Laser and Light Therapies

40 citations , February 2012 in “Dermatology Online Journal”

Lasers might help hair growth in some alopecia cases, but more research is needed to confirm their effectiveness and safety.

research Update on the Pathogenesis, Genetics, and Medical Treatment of Patterned Hair Loss

19 citations , November 2010 in “PubMed”

New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.

research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

126 citations , April 2010 in “British Journal of Dermatology”

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

research Histopathology of Alopecia: A Clinicopathological Approach to Diagnosis

170 citations , January 2010 in “Histopathology”

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss

77 citations , August 2009 in “British Journal of Dermatology”

Aromatase gene variation may increase female hair loss risk.

research Comparing the Therapeutic Effects of Finasteride Gel and Tablet in Treatment of Androgenetic Alopecia

57 citations , January 2009 in “Indian Journal of Dermatology, Venereology and Leprology”

research Dermoscopy in Female Androgenic Alopecia: Method Standardization and Diagnostic Criteria

129 citations , January 2009 in “International Journal of Trichology”

Trichoscopy can diagnose female hair loss with high accuracy by looking for specific patterns in hair and scalp appearance.

research Hair Loss in Women

129 citations , October 2007 in “The New England Journal of Medicine”

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

research A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification

125 citations , July 2007 in “Journal of The American Academy of Dermatology”

The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.

research Female Pattern Hair Loss: Current Treatment Concepts

50 citations , January 2007 in “PubMed”

Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.

research Follicular Miniaturization in Female Pattern Hair Loss: Clinicopathological Correlations

100 citations , November 2006 in “British Journal of Dermatology”

Hair loss severity relates to increased miniaturization in female pattern hair loss.

research Androgenetic Alopecia in Adolescents: A Report of 43 Cases

35 citations , October 2006 in “Journal of Dermatology”

Teen hair loss common in boys, linked to family history and mild symptoms.

research Effective Treatment of Female Androgenic Alopecia with Dutasteride

33 citations , September 2005 in “PubMed”

Dutasteride successfully treated a woman's hair loss when other treatments failed.

research Melatonin Increases Anagen Hair Rate in Women With Androgenetic Alopecia or Diffuse Alopecia: Results of a Pilot Randomized Controlled Trial

78 citations , February 2004 in “British Journal of Dermatology”

Melatonin helps hair growth in women with hair loss.

research Minoxidil: Mechanisms of Action on Hair Growth

397 citations , February 2004 in “British Journal of Dermatology”

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

research Androgenetic Alopecia in Women

139 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

Androgenetic alopecia in women needs more research and better management strategies.

research Female Pattern Hair Loss

226 citations , September 2001 in “Journal of The American Academy of Dermatology”

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

research Female Pattern Hair Loss: Clinical Features and Potential Hormonal Factors

10 citations , September 2001 in “Journal of The American Academy of Dermatology”

Hormonal factors may affect female hair loss, needing further research and treatment ideas.

research The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women

157 citations , July 2001 in “British Journal of Dermatology”

AGA more common in men, Koreans have lower rates and unique patterns.

research Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss

234 citations , February 2001 in “British Journal of Dermatology”

FPHL affects hair density and diameter, causing visible hair loss in older women.

research Role of Androgens in Female-Pattern Androgenetic Alopecia, Either Alone or Associated with Other Symptoms of Hyperandrogenism

47 citations , December 2000 in “Archives of Dermatological Research”

Androgens significantly affect female hair loss, and hormonal treatments may help.

research Androgenetic Alopecia and Microinflammation

131 citations , August 2000 in “International Journal of Dermatology”

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

research Patterned Androgenic Alopecia in Women

130 citations , May 1988 in “Journal of The American Academy of Dermatology”

"Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.

research Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex

666 citations , September 1977 in “British Journal of Dermatology”

Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.

15 / 15 results

research Platelet Rich Plasma Application by Dermapen Microneedling and Intradermal Point-by-Point Injection Methods, and Their Comparison with Clinical Findings and Trichoscan in Patients with Androgenetic Alopecia

3 citations , October 2021 in “Dermatologic Therapy”

research Results of Low-Level Laser Therapy in the Treatment of Hair Growth: An Egyptian Experience

2 citations , April 2021 in “Dermatologic Therapy”

Low-level laser therapy helps increase hair growth in female pattern hair loss but not in telogen effluvium.

research Systemic Dexpanthenol as a Novel Treatment for Female Pattern Hair Loss

5 citations , April 2021 in “Journal of Cosmetic Dermatology”

Dexpanthenol improves hair growth and satisfaction in women without side effects.

research Lyophilized Growth Factor Intralesional Injection in Female Pattern Hair Loss: A Clinical and Trichoscopic Study

February 2021 in “Dermatologic Therapy”

Injections improve hair growth, density, and thickness in women safely.

research Autologous Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia: Results of a 54-Patient Prospective Study

January 2021 in “Skinmed”

Platelet-Rich Plasma injections can effectively reduce hair thinning and loss, especially in women.

research Combination Therapy to Treat Asian Female Pattern Hair Loss

August 2019 in “Journal of Cosmetics, Dermatological Sciences and Applications”

research Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia Patients

14 citations , August 2019 in “Journal of Cosmetic Dermatology”

PRP therapy safely improves hair growth in people with hair loss.

research Platelet-Rich Plasma on Female Androgenetic Alopecia: Tested on 10 Patients

25 citations , February 2019 in “Journal of Cosmetic Dermatology”

PRP injections increase hair density and diameter in female androgenetic alopecia patients.

research Clinical Efficacy of Oral Administration of Finasteride at a Dose of 2.5 mg/Day in Women with Female Pattern Hair Loss

13 citations , March 2018 in “Dermatologic Therapy”

Finasteride 2.5 mg/day can effectively treat female hair loss.