Cedrol-Loaded Dissolvable Microneedles Based on Flexible Backing for Promoting Hair Growth

    August 2023 in “ Expert opinion on drug delivery ”
    Yanjun Zhou, Luan Jia, Guangshuai Zhang … Ning Li
    Studysummary This study found that cedrol-loaded dissolvable microneedles efficiently delivered cedrol to the deep dermis, effectively promoting hair growth in C57BL/6 mice, suggesting a promising strategy for treating hair loss.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

    1. Duo-Role Platelet-Rich Plasma: Temperature-Induced Fibrin Gel and Growth Factors' Reservoir for Microneedles to Promote Hair Regrowth Journal of Advanced Research · 2023
    2. CircAGK Regulates High Dihydrotestosterone-Induced Apoptosis in DPCs Through the miR-3180-5p/BAX Axis The FASEB Journal · 2023
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    4. Comparison of Oral Minoxidil, Finasteride, and Dutasteride for Treating Androgenetic Alopecia Journal of Dermatological Treatment · 2022
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    6. Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model Acta Biomaterialia · 2022
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    8. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021
    9. Hair Growth Promoting Activity of Cedrol Nanoemulsion in C57BL/6 Mice and Its Bioavailability Molecules · 2021
    10. Autologous Activated Platelet-Rich Plasma (AA-PRP) and Non-Activated (A-PRP) in Hair Growth: A Retrospective, Blinded, Randomized Evaluation in Androgenetic Alopecia Expert Opinion on Biological Therapy · 2020
    11. Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia BioMed Research International · 2020
    12. Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia Journal of Controlled Release · 2019
    13. Transcutaneous Implantation of Valproic Acid-Encapsulated Dissolving Microneedles Induces Hair Regrowth Biomaterials · 2018
    14. Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia Journal of Visualized Experiments · 2018
    15. Hair Growth Promotion Effect of Cedrol Cream and Its Dermatopharmacokinetics RSC Advances · 2018
    16. Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation Nature cell biology · 2017
    17. Hair Growth Promoting Activity of Cedrol Isolated from the Leaves of Platycladus Orientalis Biomedicine & Pharmacotherapy · 2016
    18. Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model Annals of Dermatology · 2016
    19. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012