Lasers in the Management of Alopecia: A Review of Established Therapies and Advances in Treatment

    April 2024 in “ Lasers in medical science ”
    Philippe Jean‐Pierre, Anika Pulumati, Eli Kasheri … Keyvan Nouri
    Studysummary This study reviews the use of lasers and light therapies as treatment options for managing the two most common types of alopecia—androegenetic alopecia and alopecia areata—highlighting that existing FDA-approved drugs like minoxidil and finasteride are partially effective, necessitating additional therapeutic approaches.
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    Research cited in this study 28

    1. Alopecia Areata: Current Treatments and New Directions American Journal of Clinical Dermatology · 2023
    2. Evaluation of Fractional Carbon Dioxide Laser Alone Versus Its Combination With Betamethasone Valerate in Treatment of Alopecia Areata: A Clinical and Dermoscopic Study Archives of dermatological research · 2022
    3. Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities Signal Transduction and Targeted Therapy · 2022
    4. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    5. Complications of Hair Transplant Procedures: Causes and Management Indian Journal of Plastic Surgery/Indian journal of plastic surgery · 2021
    6. Treatments for Alopecia Areata: A Systematic Review and Network Meta-Analysis Dermatologic therapy · 2021
    7. Complications with Hair Transplantation Facial Plastic Surgery Clinics of North America · 2020
    8. The Use of a 1,540 nm Fractional Erbium-Glass Laser in the Treatment of Alopecia Areata Lasers in surgery and medicine · 2019
    9. Topical Calcipotriol vs Narrowband Ultraviolet B in Treatment of Alopecia Areata: A Randomized-Controlled Trial Archives of Dermatological Research · 2019
    10. Alopecia Totalis Treated with 1064 nm Picosecond Nd:YAG Laser: A Case Report Applied sciences · 2019
    11. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    12. Enhancing Hair Growth in Male Androgenetic Alopecia by a Combination of Fractional CO2 Laser Therapy and Hair Growth Factors Lasers in Medical Science · 2017
    13. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    14. Androgenetic Alopecia: A Review Endocrine · 2017
    15. Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases Journal of cosmetology & trichology · 2016
    16. Visible Red Light Enhances Physiological Anagen Entry In Vivo And Has Direct And Indirect Stimulatory Effects In Vitro Lasers in surgery and medicine · 2014
    17. Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study American Journal of Clinical Dermatology · 2014
    18. Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial Dermatologic Surgery · 2013
    19. Androgenetic Alopecia: Identification Of Four Genetic Risk Loci And Evidence For The Contribution Of WNT Signaling To Its Etiology Journal of Investigative Dermatology · 2013
    20. Narrowband Ultraviolet B Phototherapy for Alopecia Areata Photodermatology Photoimmunology & Photomedicine · 2011
    21. Fractional Photothermolysis Laser Treatment of Male Pattern Hair Loss Dermatologic Surgery · 2010
    22. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
    23. HairMax LaserComb Laser Phototherapy Device in the Treatment of Male Androgenetic Alopecia Clinical Drug Investigation · 2009
    24. Use of the Pulsed Infrared Diode Laser (904 nm) in the Treatment of Alopecia Areata Journal of cosmetic and laser therapy · 2006
    25. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    26. 308-Nm Excimer Laser Therapy in Alopecia Areata Journal of the American Academy of Dermatology · 2004
    27. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    28. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001

    Related research 5

    1. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    2. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    3. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    4. Effectivity of Minoxidil as a Treatment for Alopecia Areata DOAJ (DOAJ: Directory of Open Access Journals) · 2013
    5. Hair Loss in Women with Hyperandrogenism: Four Cases Responding to Finasteride Journal of The American Academy of Dermatology · 2002