Minoxidil Cyclodextrin Complexes and Their Inclusion in Transfersomes for the Enhancement of Therapeutic Effect on Androgenic Alopecia

    Xia Kong, Xiaoya Pang, Ruifen Wang … Qingping Tian
    Studysummary In this study, the researchers reported that minoxidil-loaded transfersomes using a cyclodextrin strategy significantly increased drug stability, skin permeation, and hair regrowth in a mouse model of androgenetic alopecia compared to traditional formulations and commercial tinctures.
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    Research cited in this study 23

    1. The Preparation of High Minoxidil Loaded Transfersomes and Its Gel for Effective Topical Treatment of Alopecia Journal of Drug Delivery Science and Technology · 2023
    2. Alpinetin Promotes Hair Regeneration via Activating Hair Follicle Stem Cells Chinese medicine · 2022
    3. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    4. Neural Progenitor Cell-Derived Nanovesicles Promote Hair Follicle Growth via miR-100 Journal of nanobiotechnology · 2021
    5. The Hydroxypropyl-β-Cyclodextrin-Minoxidil Inclusion Complex Improves the Cardiovascular and Proliferative Adverse Effects of Minoxidil in Male Rats: Implications in the Treatment of Alopecia Pharmacology Research & Perspectives · 2020
    6. Exploring the Potential of Minoxidil Tretinoin Liposomal-Based Hydrogel for Topical Delivery in the Treatment of Androgenic Alopecia Cutaneous and Ocular Toxicology · 2019
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    8. Scaffold-Assisted Artificial Hair Implantation in a Rat Model JAMA Facial Plastic Surgery · 2017
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    14. Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia International Journal of Nanomedicine · 2014
    15. New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment Drug Development and Industrial Pharmacy · 2014
    16. Regenerative Medicine and Hair Loss: How Hair Follicle Culture Has Advanced Our Understanding of Treatment Options for Androgenetic Alopecia Regenerative Medicine · 2013
    17. Niosomes as a Vesicular Carrier for Topical Administration of Minoxidil: Formulation and In Vitro Assessment Drug Delivery and Translational Research · 2013
    18. Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model Journal of Dermatological Science · 2013
    19. 5α-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment Journal of Ethnopharmacology · 2011
    20. Fructus Panax Ginseng Extract Promotes Hair Regeneration in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    21. The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams International Journal of Pharmaceutics · 2010
    22. Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution Contact Dermatitis · 2005
    23. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002