Study on the Expression Patterns of Inner Root Sheath-Specific Genes in Tan Sheep Hair Follicle During Different Developmental Stages

    July 2024 in “ Gene ”
    An Shi, Jiangjiang Lv, Qing Ma … Jinzhong Tao
    Studysummary This study analyzed inner root sheath-specific genes in Tan sheep during various growth stages, finding peak expression at birth. The pattern of genes KRT71, KRT72, and TCHH is consistent with wool crimp, potentially influencing wool morphology.
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    Research cited in this study 21

    1. Spatiotemporal Expression and Haplotypes Identification of KRT84 Gene and Their Association with Wool Traits in Gansu Alpine Fine-Wool Sheep Genes · 2024
    2. Histological Characteristics of Hair Follicles at Different Hair Cycle and In Vitro Modeling of Hair Follicle-Associated Cells of Yak (Bos Grunniens) Frontiers in veterinary science · 2023
    3. Gene Network Analysis Reveals Candidate Genes Related to Hair Follicle Development in Sheep BMC genomics · 2022
    4. Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending Frontiers in cell and developmental biology · 2022
    5. Skin Transcriptome Analysis Identifies Key Genes Underlying Fur Development in Chinese Tan Sheep During Birth and Er-Mao Periods Gene · 2022
    6. The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes International journal of molecular sciences · 2021
    7. Dynamic Changes of Genomic Methylation Profiles at Different Growth Stages in Chinese Tan Sheep Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · 2021
    8. Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep BMC Biology · 2021
    9. A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle Genes · 2021
    10. Effect of Nutritional Restriction on the Hair Follicles Development and Skin Transcriptome of Chinese Merino Sheep Animals · 2020
    11. An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses Scientific Reports · 2018
    12. Variation in the Ovine Trichohyalin Gene and Its Association with Wool Curvature Small Ruminant Research · 2017
    13. Association Analysis of Polymorphisms in Six Keratin Genes with Wool Traits in Sheep Asian-Australasian journal of animal sciences · 2017
    14. The Biology And Genetics Of Curly Hair Experimental Dermatology · 2017
    15. Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits Genes · 2017
    16. Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome American journal of human genetics · 2016
    17. Transcriptome Profile at Different Physiological Stages Reveals Potential Mechanism for Curly Fleece in Chinese Tan Sheep PloS one · 2013
    18. Expression Patterns of Keratin Intermediate Filament and Keratin Associated Protein Genes in Wool Follicles Differentiation · 2009
    19. Trichohyalin Mechanically Strengthens the Hair Follicle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    20. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    21. The Fate of Trichohyalin Journal of biological chemistry/˜The œJournal of biological chemistry · 1997

    Related research 5

    1. TRPV3 Gain-of-Function Mutation Impairs Differentiation of Hair Follicle Inner Root Sheath ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    2. Functional Analysis of Keratin Components in the Mouse Hair Follicle Inner Root Sheath British Journal of Dermatology · 2004
    3. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    4. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    5. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981