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    Efficacy of Topical Minoxidil and Oral Spironolactone Versus Minoxidil and Finasteride in Androgenic Alopecia

    August 2023 in “ Journal of Cosmetic Dermatology ”
    Afsaneh Sadeghzadeh-Bazargan, Zohreh Tavana, Abbas Dehghani … Azadeh Goodarzi
    Studysummary This study found that combining minoxidil and spironolactone was more effective for hair density and severity of hair loss in women with androgenic alopecia compared to minoxidil and finasteride, with no serious adverse effects reported.
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    Research cited in this study 25

    1. Dermoscopic Evaluation of the Efficacy of Combination of Topical Spironolactone 5% and Minoxidil 5% Solutions in the Treatment of Androgenetic Alopecia: A Cross-Sectional Comparative Study Journal of Cosmetic Dermatology · 2022
    2. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator-Blinded, Randomized Trial Frontiers in Medicine · 2022
    3. Prevalence of Female Pattern Hair Loss in Postmenopausal Women: A Cross-Sectional Study Menopause · 2022
    4. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    5. Pumpkin Seed Oil vs. Minoxidil 5% Topical Foam for the Treatment of Female Pattern Hair Loss: A Randomized Comparative Trial Journal of Cosmetic Dermatology · 2021
    6. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021
    7. A Novel Topical Combination of Minoxidil and Spironolactone for Androgenetic Alopecia: Clinical, Histopathological, and Physicochemical Study Dermatologic Therapy · 2020
    8. A Pilot Evaluation of Scalp Skin Wounding to Promote Hair Growth in Female Pattern Hair Loss International Journal of Women's Dermatology · 2020
    9. Implications of Cigarette Smoking on Early-Onset Androgenetic Alopecia: A Cross-Sectional Study Journal of Cosmetic Dermatology · 2020
    10. Cross-Sectional Quality of Life Assessment in Patients with Androgenetic Alopecia Dermatologic Therapy · 2020
    11. Topical Finasteride Versus Topical Spironolactone in the Treatment of Androgenetic Alopecia The Medical Journal of Cairo University · 2020
    12. Spironolactone for Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2020
    13. Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum] Drug Design Development and Therapy · 2020
    14. The Effectiveness of Finasteride and Dutasteride Used for 3 Years in Women with Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2014
    15. Quality of Life in Women with Female Pattern Hair Loss and the Impact of Topical Minoxidil Treatment Experimental and Therapeutic Medicine · 2013
    16. Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women International Journal of Trichology · 2013
    17. Efficacy of Finasteride 1.25 mg on Female Pattern Hair Loss: Pilot Study Annals of Dermatology · 2012
    18. 5 mg/Day Finasteride Treatment for Normoandrogenic Asian Women with Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2010
    19. Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss PubMed · 2010
    20. Successful Treatment of Female-Pattern Hair Loss with Spironolactone in a 9-Year-Old Girl Australasian Journal of Dermatology · 2009
    21. Treatment of Female Pattern Hair Loss with a Combination of Spironolactone and Minoxidil Australasian Journal of Dermatology · 2007
    22. Finasteride Treatment of Female Pattern Hair Loss Archives of Dermatology · 2006
    23. Evaluation and Treatment of Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    24. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    25. Finasteride Treatment of Patterned Hair Loss in Normoandrogenic Postmenopausal Women Dermatology · 2004

    Related research 9

    1. Efficacy of Topical Minoxidil and Oral Spironolactone Versus Minoxidil and Finasteride in Androgenic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Combination Therapy in Female Pattern Hair Loss Journal of Cosmetic and Laser Therapy · 2023
    3. Platelet-Rich Plasma as a Method of Treatment of Androgenetic Alopecia in Men: A Case Report Journal of Face Aesthetics · 2020
    4. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients Dermatology practical & conceptual · 2020
    5. Treatment of Female Pattern Hair Loss with the Androgen Receptor Antagonist Flutamide Australasian Journal of Dermatology · 2011
    6. A Review of Hormonal Therapy for Female Pattern (Androgenic) Alopecia Dermatology Online Journal · 2008
    7. Treatment of Female Pattern Hair Loss with a Combination of Spironolactone and Minoxidil Australasian Journal of Dermatology · 2007
    8. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    9. Managing Hair Loss Current Therapeutics · 1998