The Hair Follicle Enigma

    March 2017 in “ Experimental Dermatology ”
    Bruno Bernard
    Studysummary This review discusses various aspects of hair follicle biology and highlights unresolved questions and potential new research avenues, but presents no new experimental findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 50

    1. Hair Follicle Stem Cell Cultures Reveal Self-Organizing Plasticity of Stem Cells and Their Progeny The EMBO Journal · 2016
    2. Keratin Network Modifications Lead to the Mechanical Stiffening of the Hair Follicle Fiber Proceedings of the National Academy of Sciences of the United States of America · 2016
    3. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    4. A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features Nature Communications · 2016
    5. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    6. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
    7. The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015
    8. Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis Journal of biological chemistry/˜The œJournal of biological chemistry · 2014
    9. FGF5 Is a Crucial Regulator of Hair Length in Humans Proceedings of the National Academy of Sciences of the United States of America · 2014
    10. A Newly Discovered Linkage Between Proteoglycans and Hair Biology: Decorin Acts as an Anagen Inducer Experimental Dermatology · 2014
    11. Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges BioEssays · 2014
    12. Investigation of Four Novel Male Androgenetic Alopecia Susceptibility Loci: No Association with Female Pattern Hair Loss Archives of Dermatological Research · 2013
    13. Evidence for a Polygenic Contribution to Androgenetic Alopecia British Journal of Dermatology · 2013
    14. Position Effect on FGF13 Associated with X-Linked Congenital Generalized Hypertrichosis Proceedings of the National Academy of Sciences of the United States of America · 2013
    15. Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers Journal of Investigative Dermatology · 2013
    16. The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias The FASEB Journal · 2012
    17. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    18. Hairy Tale of Signaling in Hair Follicle Development and Cycling Seminars in cell & developmental biology · 2012
    19. Estrogen Leads to Reversible Hair Cycle Retardation Through Inducing Premature Catagen and Maintaining Telogen PLOS ONE · 2012
    20. A Novel Monilethrix Mutation in Coil 2A of KRT86 Causing Autosomal Dominant Monilethrix with Incomplete Penetrance British Journal of Dermatology · 2012
    21. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    22. The Human Hair Follicle, A Bistable Organ? Experimental Dermatology · 2012
    23. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    24. Integral Hair Lipid in Human Hair Follicle Journal of dermatological science · 2011
    25. LPA-Producing Enzyme PA-PLA1α Regulates Hair Follicle Development by Modulating EGFR Signaling The EMBO Journal · 2011
    26. Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis PloS one · 2011
    27. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    28. De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle Journal of Investigative Dermatology · 2010
    29. Chronological Aging of Human Hair Keratin Fibers International Journal of Cosmetic Science · 2010
    30. APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex Nature · 2010
    31. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    32. FGFR2 Is Associated With Hair Thickness In Asian Populations Journal of human genetics · 2009
    33. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    34. Heparanase 1: A Key Participant of Inner Root Sheath Differentiation Program and Hair Follicle Homeostasis Experimental Dermatology · 2008
    35. Prostanoid Receptors in Anagen Human Hair Follicles Experimental dermatology · 2007
    36. Human Hair Keratin Network And Curvature International Journal of Dermatology · 2007
    37. Prostaglandin Metabolism in Human Hair Follicle Experimental Dermatology · 2007
    38. Abnormalities in the Hair Morphology of Patients with Some but Not All Types of Mucopolysaccharidoses European journal of pediatrics · 2007
    39. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006
    40. Immunofluorescence Analysis of the Basement Membrane Zone Components in Human Anagen Hair Follicles Experimental Dermatology · 2003
    41. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003
    42. Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection British Journal of Dermatology · 2002
    43. Kenogen Dermatology · 2002
    44. Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth Acta dermato-venereologica · 2000
    45. Modeling the Dynamics of Human Hair Cycles by a Follicular Automaton Proceedings of the National Academy of Sciences · 2000
    46. Expression of Retinoid Nuclear Receptor Superfamily Members in Human Hair Follicles and Its Implication in Hair Growth Acta Dermato Venereologica · 1997
    47. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    48. Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue Journal of Investigative Dermatology · 1993
    49. Expression of the L-Fucose Moiety on Infrainfundibular Follicular Keratinocytes of Terminal Follicles, Its Decreased Expression on Vellus and Indeterminate Follicles of Androgenetic Alopecia, and Re-Expression in Drug-Induced Hair Regrowth Journal of Investigative Dermatology · 1992
    50. Glycoconjugate Expression of Cells of Human Anagen Hair Follicles During Keratinization The Anatomical Record · 1990