Search

everythinglearnresearchcommunity

for

Search:↓

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Minoxidil activation by hair enzymes predicts treatment success for female hair loss.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Topical booster improves hair loss treatment effectiveness.

The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.

Selective breeding caused the unique curly hair in Mangalitza pigs.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.

Daily low-dose aspirin lowers minoxidil's effectiveness for hair loss treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.