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This study identified and characterized several long noncoding RNAs in Cashmere goats, revealing complex regulatory roles in hair follicle development and growth, particularly within the Wnt signaling pathway.

This study found that morroniside enhanced hair follicle growth and transition through the Wnt/β-catenin signaling pathway in a mouse model, suggesting its potential as a treatment for hair loss.

In this study, DHT was observed to have varying effects on hair follicle growth and related protein expression depending on concentration, with the Wnt/β-catenin pathway potentially playing a significant role.

This study generated FGF5-knockout Dorper sheep using the CRISPR/Cas9 system, resulting in significantly increased fine-wool and active hair-follicle density, and explored downstream signaling pathways for potential applications in androgen alopecia treatment.

This study found that adding Wnt-10b to the culture medium of dermal papilla cells maintained their ability to induce hair follicles over 100 days in vitro.

In this study, topical methyl vanillate application increased hair count and hair mass index in women with androgenetic alopecia by enhancing WNT10B expression, suggesting a potential new treatment strategy.

This study suggests that miRNAs, particularly miR-195-5p, may regulate the loss of hair follicle inductivity in cultured dermal papilla cells by suppressing the Wnt/β-catenin pathway.

This study found that Sargassum muticum extract and apo-9′-fucoxanthinone promoted hair growth in rat and mouse models by increasing dermal papilla cell proliferation and activating certain signaling pathways.

The study suggests that abnormal activation of hair follicle stem cells and Wnt10b/β-catenin signaling may contribute to the development of sebaceous neoplasms.

This review summarizes existing knowledge of how the WNT signaling pathway affects mesenchymal stem cells under various conditions, highlighting challenges and mechanisms for clinical applications.

This study found that bovine lactoferrin promotes hair growth in mice by enhancing dermal papilla cell proliferation through the Erk/Akt and Wnt signaling pathways.

This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.

This study developed a mouse model to monitor hair follicle cycling macroscopically through live bioluminescence imaging, enabling detailed analysis of hair cycle and propagation dynamics influenced by environmental factors.

This study found that insulin promotes corneal epithelial wound healing and nerve recovery in diabetic mice through Wnt signaling, suggesting its potential as a protective factor for diabetic corneal damage.

This review discusses various Wnt pathway modulators developed between 2014 and 2020, highlighting their potential as treatments for diseases like cancer and osteoarthritis, but reports no new clinical results.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.

This study suggests that the long noncoding RNA H19 helps dermal papilla cells maintain their hair follicle-inducing ability by activating the Wnt signaling pathway, potentially offering a therapeutic target for androgenetic alopecia.

This study found that dihydrotestosterone (DHT) suppresses prostaglandin E2 and TGF-β induced IGF-I gene promoter activity in osteoblasts, suggesting complex interactions among bone growth regulators and potential complications from anabolic steroid use.

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

This study found that 1,550-nm Er:Glass fractional laser treatment increased hair density and shaft diameter in patients with androgenetic alopecia, but did not up-regulate Wnt10A and IGF-1 mRNA expression.

In this study, rice bran mineral extract increased expression of anagen-related proteins and decreased inflammatory markers in human dermal papilla cells, suggesting potential for hair growth enhancement and prevention of hair loss.

Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.

This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.

In this animal study, PRF enhanced the repair of chronic wounds in rats by reducing inflammation and promoting collagen deposition and new blood vessel formation, potentially through activating the Wnt/β-catenin signaling pathway.

This study concluded that controlled micro-injury induces hair regeneration and vitiligo repigmentation in mice, potentially through the Wnt/β-catenin pathway.

This study found that low-fluence intense pulsed light promoted hair growth in C57BL/6 mice by inducing an earlier and prolonged anagen phase and activating the WNT/β-catenin pathway.

This study found that the novel IPC analog SIG-1451 may inhibit inflammatory cytokine release in cell-based assays relevant to allergic dermatitis.

This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.

This study reports that in Rex rabbits, age affects fur quality and hair follicle traits, with the Wnt signaling pathway playing a role in their periodic hair follicle development.