Micro-Injury Induces Hair Regeneration And Vitiligo Repigmentation Through Wnt/β-Catenin Pathway

    Xiaofeng Han, Li Chang, Mao Lin, Dongwei Qi, Yuyi Wang, Deming Liu, Wei Xu, Julia Li Zhong, Qingchun Diao
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    TLDR Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.
    The study demonstrated that controlled micro-injury effectively induced hair regeneration and vitiligo repigmentation by activating specific stem cells and shifting hair follicles from the telogen to anagen phase. In a vitiligo model, micro-injury prompted melanocyte stem cells to migrate and repopulate depigmented areas. The Wnt/β-catenin pathway was identified as crucial in this regeneration process. This research suggested that micro-injury could be a promising treatment method for conditions like alopecia and vitiligo.
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