research Public Awareness of the Symptoms and Risk Factors of Thyroid Disease in Saudi Arabia
Many people in Saudi Arabia lack awareness of thyroid disease risk factors and symptoms, highlighting the need for better health education.
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research A Randomized Double-Blind Placebo-Controlled Clinical Trial to Evaluate the Effect of an Annurca Apple Supplement Formula in Androgenic Alopecia
The Annurca apple supplement significantly improved hair growth in people with hair loss.
research Biotin: Daily Intake Requirements, Sources, and Deficiency Effects
People need different amounts of biotin based on age, and not getting enough can cause health problems.
research New Developments in Our Understanding of Acne Pathogenesis and Treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research The Vitamin D Receptor as Tumor Suppressor in Skin
Vitamin D and its receptor may help prevent skin cancer.
research Novel De Novo Pathogenic Variant in the ODC1 Gene in a Girl with Developmental Delay, Alopecia, and Dysmorphic Features
The study reported a novel de novo pathogenic variant in the ODC1 gene in a 32-month-old Caucasian girl, marking the first human case with symptoms similar to those observed in a transgenic ODC1 mouse model. The identified heterozygous nonsense mutation in the ODC1 gene resulted in a premature termination of 14 amino acid residues at the protein's c-terminus. The patient exhibited phenotypic features such as developmental delay, alopecia, macrosomia, macrocephaly, spasticity, hypotonia, cutaneous vascular malformation, delayed visual maturation, and sensorineural hearing loss. Whole-exome sequencing and Sanger sequencing confirmed the mutation (c.1342 A>T), and elevated ODC protein and polyamine levels were found in the patient's red blood cells. The study suggested that the patient might benefit from treatment with α-difluoromethylornithine, an FDA-approved drug.
research Pollen Allergies in Humans and Their Dogs, Cats, and Horses: Differences and Similarities
Humans and pets share similar allergy mechanisms, and studying pet allergies can help treat both human and animal allergies.
research Prevention and Treatment of Alopecia Areata with Quercetin in the C3H/HeJ Mouse Model
Quercetin effectively treated and prevented hair loss in mice.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research Effects of Lespedeza Cuneata Aqueous Extract on Testosterone-Induced Prostatic Hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research Micronutrients in Hair Loss
Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness, and Trends
Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
research Risks of Skin, Hair, and Nail Supplements
Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.
research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research Regulatory Network of Ginsenoside Biosynthesis Under Ro Stress in the Hairy Roots of Panax Ginseng Revealed by RNA Sequencing
Ro stress hindered ginseng root growth and ginsenoside production, but increased certain hormones and affected gene regulation related to plant growth and stress responses.
research Therapeutic Use of Caffeine in Dermatology: A Literature Review
Caffeine may benefit skin and hair health but more research is needed to confirm its effectiveness in dermatology.
research Extraction of Gallic Acid and Ferulic Acid for Application in Hair Supplements
Gallic acid and ferulic acid can be sustainably extracted for hair supplements with high efficiency and stability.
research Vitamin D Receptor Gene Polymorphisms Taq-1 and Cdx-1 in Female Pattern Hair Loss
Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.
research Collagen Hydrolysate from Mozambique Tilapia Scales Improves Hair and Skin Health
Collagen from tilapia scales may improve hair and skin health by reducing stress and inflammation and encouraging hair growth.
research Suspected Adverse Reactions to Medications and Food Supplements Containing Serenoa Repens: A Worldwide Analysis of Pharmacovigilance and Phytovigilance Spontaneous Reports
Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.
research Melandrium Firmum Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice
Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
research Effect of Dietary Methylsulfonylmethane Supplementation on Growth Performance, Hair Quality, Fecal Microbiota, and Metabolome in Ragdoll Kittens
MSM supplementation in kittens improves hair quality and growth rate without harming their health.
research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services
GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.
research Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets
Plant extracts can help prevent hair loss and promote hair growth.
research Relationship Between Prepregnancy BMI and Concentrations of Iron, Calcium, and Magnesium in Serum and Hair During the First Trimester of Pregnancy in Women
Overweight or obese women before pregnancy have lower iron levels in their serum and hair during early pregnancy.
research Oral and Topical Administration of Standardized Saw Palmetto Oil Reduces Hair Fall and Improves Hair Growth in Androgenetic Alopecia Subjects: A 16-Week Randomized, Placebo-Controlled Study
Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.
research The Medicinal Activity of Lyophilized Aqueous Seed Extract of Lepidium Sativum L. in an Androgenic Alopecia Model
The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.
research Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways
Fish collagen peptides can significantly promote hair growth.
research Clinical Evaluation of Intradermal Platelet-Rich Plasma Administration Along with Oral Biotin Supplement for the Management of Androgenetic Alopecia in Adult Males: A Randomized Clinical Trial
Using platelet-rich plasma injections and biotin pills together significantly increases hair regrowth in men with hair loss.
research Application of Stem Cells in Regenerative Medicine
Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.