January 2020 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study found that Polycomb Repressive Complex 1 is crucial for maintaining stem cell identity across different lineages, but its loss results in varied transcriptional outcomes depending on the tissue context.
66 citations
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July 2015 in “Organogenesis” This review summarizes recent findings on how Wnt signaling proteins play crucial roles in the cutaneous wound healing process but reports no new clinical results.
45 citations
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April 2013 in “Cell Transplantation” In this study, the researchers reported that activin B combined with bone marrow-derived mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats by promoting cell migration through the ERK and JNK pathways.
74 citations
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April 2024 in “Cell Communication and Signaling” This review highlights the role of the Wnt/β-catenin signaling pathway in wound healing, particularly in diabetic ulcers, discussing its interactions with other pathways and potential therapeutic strategies targeting this pathway, such as photobiomodulation.
4 citations
,
January 2011 in “Chinese Herbal Medicines” This study found that improving the solubility of wogonin can significantly enhance its bioavailability in Beagle dogs.
January 2026 in “Medicina” In this study, researchers documented the immunohistochemical distribution of CD34 in basal cell carcinoma and found distinct patterns of CD34 expression, with variations in CD34 positivity between different areas of BCC tumor stroma and adjacent skin regions.
41 citations
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July 2019 in “Clinical Cosmetic and Investigational Dermatology” This paper explores the complex immune processes and cellular diversity that enable the skin to heal and resist invasion, and highlights its potential as a model for studying regeneration.
1 citations
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October 2020 in “Research Square (Research Square)” This study found that abnormal Wnt signalling in stem cells may contribute to blackhead formation in acne by inhibiting cell differentiation and causing cell accumulation in the junctional zone.
9 citations
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June 2022 in “Composites. Part B, Engineering” In this study, a novel silver nanowires/collagen I/bacterial cellulose dressing demonstrated strong antibacterial activity and enhanced wound healing capabilities, while showing improved cytocompatibility and mechanical properties compared to traditional silver nanowire-based dressings.
This study identified 193 plasma proteins associated with prostate cancer risk, validating 20 high-risk proteins including KLK3, and pinpointed potential drug targets like HSPB1, RRM2B, and PSCA through genetic analysis, offering new insights for biomarkers and treatments.
37 citations
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March 2020 in “Molecules” This review outlines the adverse effects of glucocorticoid excess on bones, adipose tissue, brain, and skin, with a focus on the Wnt/β-catenin pathway, and reports no new research findings.
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that specific inhibition of the classical complement pathway with BIVV009 prevented C3 deposition along the dermal-epidermal junction in bullous pemphigoid, reflecting its potential efficacy.
27 citations
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May 2018 in “Journal of Dermatological Science” This study suggests that M2 macrophages play a key role in promoting wound-induced hair neogenesis in mice by producing growth factors like Igf1 and Fgf2.
1 citations
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June 2021 in “Problems of Cryobiology and Cryomedicine” In this study on rats, CBF injections demonstrated significant wound healing effects and improved recovery after skin cryoablation, similar to the effects observed with Actovegin.
8 citations
,
August 1987 in “The Journal of Dermatology” This study reports that the monoclonal antibody BKN-1 specifically stained basal cell epithelioma cells and certain normal skin structures, indicating a similarity in keratin expression between the tumor and follicular epithelium below the isthmus portion.
4 citations
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October 2021 in “Journal of Cellular and Molecular Medicine” This study observed that mature neutrophils and their extracellular traps inhibit wound-induced hair follicle neogenesis in mice, despite being stimulated by pro-regenerative cues.
April 2024 in “Journal of microbiology and biotechnology” The authors will correct the table to show the right antibody information.
April 2021 in “Institutional Repositories DataBase (IRDB)” This study reported that high-intensity red LED irradiation increased osteogenic differentiation and mineralization of human bone marrow mesenchymal stem cells, potentially through Wnt/β-catenin pathway activation.
September 2026 in “Stem Cell Reviews and Reports” Bulge progenitor cells show promise for regenerating hair follicles and increasing hair density.
November 2018 in “The European research journal” In this study, researchers found that patients with alopecia areata who had nail involvement or a history of autoimmune disease showed significantly higher red cell distribution width levels.
January 2025 in “Cell Communication and Signaling” This study reviews the role of the zinc finger protein CXXC5 in cellular signaling and its implications for cancer, discussing how its dysregulation is linked to various physiological and pathological processes, as well as potential therapies targeting CXXC5.
86 citations
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November 2015 in “Journal of Gastroenterology” This study reported that the NUDT15 R139C genetic variant was significantly associated with thiopurine-induced leukocytopenia in Japanese inflammatory bowel disease patients, independent of 6-thioguanine nucleotide levels.
28 citations
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September 2020 in “International Journal of Molecular Sciences” This study concluded that leucocyte-rich PRP has a continuous stimulatory effect on human fibroblast cells, enhancing their proliferation, migration, and impacting gene expression of the extracellular matrix and adhesion molecules.
23 citations
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July 2021 in “International journal of laboratory hematology” This report describes an 84-year-old man who developed severe autoimmune hemolytic anemia after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine, highlighting a potential, rare side effect without proving causation.
14 citations
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November 2016 in “Lupus” In this retrospective study of adolescents with recalcitrant cutaneous lupus, lenalidomide treatment resulted in complete or near resolution of skin symptoms within 6 months, while allowing for a reduction in prednisone dosage.
11 citations
,
March 2013 in “Journal of Ophthalmic Inflammation and Infection” This report describes two cases of VKH disease and SO where severe alopecia, likely due to incomplete treatment, improved following systemic steroid therapy.
9 citations
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January 2016 in “Case Reports in Medicine” This study reported two cases of ryzophagia among nonpregnant women in the US, with symptoms resolving after iron dextran therapy, suggesting a link with iron deficiency.
6 citations
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January 2000 in “The Journal of Trace Elements in Experimental Medicine” In this study, an 11-year-old girl with acrodermatitis enteropathica showed significant improvement in symptoms after oral zinc therapy.
4 citations
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March 2003 in “International Journal of Dermatology” In this case report, a white man with mental retardation and suspected sensory neural hearing loss experienced resolution of cystic lesions and partial regeneration of facial fat after 1.5 months of pimozide therapy.
3 citations
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June 2018 in “Internal Medicine” In this study, a patient with Cronkhite-Canada syndrome complicated by severe sepsis and disseminated intravascular coagulation was successfully treated using combined therapies, including recombinant human soluble thrombomodulin, despite the absence of a standard treatment regimen for CCS.