A Facile, Biosynthetic Design Strategy for High-Performance Multifunctional Bacterial Cellulose-Based Dressing

    June 2022 in “ Composites. Part B, Engineering ”
    Zhifei Yang, Le Ma, Xiao Han, Xiaowei Xun, Tanmou Li, Keke Duan, Xiaoming Hu, Yizao Wan, Haiyong Ao
    TLDR The new dressing with silver nanowires and collagen on bacterial cellulose heals wounds effectively with less toxicity and good antibacterial properties.
    The document discusses the creation of a novel wound dressing made from bacterial cellulose (BC), silver nanowires (AgNWs), and collagen I (Col-I). The dressing was created by introducing AgNWs into the BC structure using a step-by-step in situ biosynthesis method, then immersing the resulting AgNW/BC in a type I collagen solution. The collagen was attached to the surface of the BC network structure, slowing down the release of silver ions and improving the cytocompatibility of the dressing. The final AgNW/CBC dressing contained 10.2% g/g of AgNWs and 22.6% g/g of Col-I. This dressing exhibited excellent cytocompatibility, making it a promising solution for treating skin lesions and wounds.
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