Comparative Evaluation of Wound Healing Effect of Cord Blood Low Molecular Weight Fraction (Below 5 kDa) and Actovegin Drug in Skin Cryolesions

June 2021 in “ Problems of Cryobiology and Cryomedicine ”

Oleksandr K. Gulevsky, Наталія Моісєєва, Olga Gorina, Yuliia Akhatova

cord blood fraction Actovegin wound healing skin cryolesions tissue regeneration hypervascularization sclerotic processes

TLDR Cord blood fraction heals skin wounds as effectively as Actovegin.

The study compared the wound healing effects of a low molecular weight fraction (below 5 kDa) from cattle cord blood (CBF) and the drug Actovegin on skin cryolesions in rats. Both treatments were found to accelerate tissue regeneration, improve blood parameters, and enhance vascularization in the injured area, thereby preventing sclerotic processes. The effects of CBF were comparable to those of Actovegin, suggesting its potential as an effective therapy for cryolesions.

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Comparative Evaluation of Wound Healing Effect of Cord Blood Low Molecular Weight Fraction (Below 5 kDa) and Actovegin Drug in Skin Cryolesions

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