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570-600 / 1000+ resultsresearch Thallium in rodenticide- banned or not..!!!- Two case reports
This report describes two cases of thallium poisoning with gastrointestinal symptoms, peripheral neuropathy, and alopecia, which were effectively treated using activated charcoal, potassium chloride, and hemodialysis.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
research The effect of St John’s Wort treatment on finasteride metabolism and identification of new finasteride metabolites in humans
St John’s Wort can change how finasteride works in the body.
research Janus kinase inhibitor as a therapeutic option in alopecia areata. Case report
In this study, a 24-year-old patient with severe alopecia areata showed an excellent clinical response to the JAK inhibitor tofacitinib after one month, following unsuccessful previous treatments.
research P175 The effects of biotin supplementation on alopecia in rats which were administrated to valproic acid
Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
research Arrhythmia phenotypes in hair-loss therapies: insights from minoxidil and finasteride reports in eudravigilance
This study found that minoxidil and finasteride, commonly used for androgenetic alopecia, were associated with different arrhythmia profiles in adverse event reports: minoxidil predominantly with supraventricular arrhythmias and finasteride primarily with ventricular arrhythmias in men.
research Core–Sheath Nanofibers From a Modified Coaxial Electrospinning for Transdermal Delivery of Finasteride
In this study, researchers employed a modified coaxial electrospinning technique to create core-sheath nanofibers, which improved the transdermal delivery of finasteride compared to traditional monolithic nanofibers, showing enhanced penetration rates throughout the testing period.
research Balance of tofacitinib efficacy and disease flare in the treatment of alopecia universalis: A case report and review of the literature
This article discusses alopecia areata, highlighting its autoimmune nature and the lack of FDA-approved treatments, without providing new research findings.
research America - A Diversity of Life Styles.
This Phase II study found that BAY 43-9006, given at 400 mg orally twice daily, led to stable disease in 30% and tumor reduction in 40% of renal cell carcinoma patients.
research Use of the drug Wolvit® (biotin 5 mg) in treatment of defuse telogenous alopecia
In this study, the researchers reported that women with diffuse telogen alopecia who took Wolvit® (biotin 5 mg) daily for 3 months showed a significant decrease in hair in the telogen phase and an increase in hair thickness and growth speed.
research FDA vetoes labelling proposals for finasteride, dutasteride
research Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System
This study demonstrated that sodium valproate accelerates skin healing and reduces necrosis in a rat model of skin flap potentially through mechanisms involving GABA and histone deacetylase pathways.
research [Adverse effects of valproic acid in epileptic infants and adolescents].
This study observed that while valproic acid treatment in children led to occasional mild clinical and laboratory side effects, no correlation with drug plasma levels was found.
research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.
research Influence of an iplatelant therapy with P2Y12 receptor inhibitors on platelet function in elderly patients with acute coronary syndrome
This study found that elderly patients with acute coronary syndrome had higher PRU rates, and ticagrelor showed greater antiplatelet efficacy compared to clopidogrel in this population.
research SUN-332 A Rare Case Of Hereditary 1,25 (OH)2D Resistant Rickets
This study highlights a rare case of vitamin D-dependent rickets type 2A caused by a heterozygous mutation in the vitamin D receptor gene, emphasizing the complexity of managing this condition with high-dose calcium and vitamin D therapy.
research An urticarial drug eruption caused by tofacitinib for alopecia universalis
A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.
research Dutasteride/finasteride
research The Malnourished Heart: An Unusual Case of Heart Failure
This case report highlights that repletion of various micronutrients, including thiamine, significantly improved heart failure symptoms and cardiac function in a malnourished patient with vitamin deficiencies.
research Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents
This review found that fulvestrant is well tolerated in postmenopausal women with hormone receptor-positive advanced breast cancer, showing lower incidence of joint disorders than non-steroidal aromatase inhibitors.
research Reversal of Alopecia Universalis by Tofacitinib: A Case Report
Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.
research UNITY INOVA NMR Spectrometer Systems Installation Planning
This study found that two-thirds of patients with persistent chronic daily headache showed significant improvement with divalproex sodium treatment, although common side effects included weight gain, tremor, hair loss, and nausea.
research A Retrospective Case-Control Study Evaluating Medications Associated with Inpatient Falls in a Single Veterans Affairs Medical Center
This study observed that certain medications, including antipsychotics, non-sedating antidepressants, and finasteride, were associated with a higher risk of inpatient falls among older adults at a Veterans Affairs Medical Center compared to matched controls.
research Outcome of intra-operative injected platelet-rich plasma therapy during follicular unit extraction hair transplant: A prospective randomised study in forty patients
This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.
research Cutaneous calcinosis of scleroderma. Successful treatment with intralesional adrenal steroids.
This report describes almost complete resolution of calcinosis and healing of associated ulcers in an 83-year-old woman with localized scleroderma after repeated intralesional steroid injections.
research Neonatal lupus syndrome in a Nigerian child
This case report describes a male infant born to a mother with systemic lupus erythematosus, presenting with neonatal lupus, who improved with conservative management and whose skin lesions resolved by 6 months of age.
research DELIRIUM WITHOUT FOCAL SIGNS RELATED TO A THALAMIC STROKE
This case report observed that delirium can be the sole symptom of a stroke, as seen in an elderly patient with a thalamic hemorrhage, highlighting the need to consider stroke in the differential diagnosis when delirium is present without focal neurological signs.
research Treatment of Alopecia in Children
This review discusses treatment options for various types of alopecia in children and reports no new clinical results; it analyzes the existing literature on safety and efficacy.
research The ginseng pimple: an inflammatory papule following ginseng consumption
This report describes a case of a 60-year-old woman experiencing inflammatory skin reactions after consuming ginseng and reviews the characteristics of its use in healthcare, although detailed descriptions of such effects are limited.