Neonatal Lupus Syndrome in a Nigerian Child

Neonatal lupus syndrome, a rare condition caused by maternal autoantibodies, was reported in a Nigerian male infant born to a mother with systemic lupus erythematosus. The infant presented at 8 weeks with a hypopigmented rash, patchy alopecia, anemia, and thrombocytopenia. Serologic tests confirmed the presence of ANA and anti-La/SSB antibodies. He was treated conservatively with blood products and topical corticosteroids, and his condition improved over 2 months, with complete resolution of skin lesions by 6 months. This case highlighted the occurrence of neonatal lupus in African settings and demonstrated that prompt treatment can manage potentially life-threatening hematological disorders effectively.