Neonatal Lupus Syndrome in a Nigerian Child

May 2012 in “ BMJ Case Reports ”

Moses Temidayo Abiodun, OO Adelowo

neonatal lupus systemic lupus erythematosus hypopigmented rash patchy alopecia anemia thrombocytopenia autoantibodies topical corticosteroids lupus hair loss skin rash blood disorder steroids

TLDR A Nigerian baby with neonatal lupus got better with treatment by 6 months.

Neonatal lupus syndrome, a rare condition caused by maternal autoantibodies, was reported in a Nigerian male infant born to a mother with systemic lupus erythematosus. The infant presented at 8 weeks with a hypopigmented rash, patchy alopecia, anemia, and thrombocytopenia. Serologic tests confirmed the presence of ANA and anti-La/SSB antibodies. He was treated conservatively with blood products and topical corticosteroids, and his condition improved over 2 months, with complete resolution of skin lesions by 6 months. This case highlighted the occurrence of neonatal lupus in African settings and demonstrated that prompt treatment can manage potentially life-threatening hematological disorders effectively.

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