Janus Kinase Inhibitor as a Therapeutic Option in Alopecia Areata: Case Report

April 2023 in “ Revista colombiana de reumatología ”

Lina María Saldarriaga Rivera, Christian David Marín Giraldo, Fabián Andrés Hernández Velasco

Janus kinase inhibitor alopecia areata tofacitinib minoxidil corticosteroids finasteride cryotherapy JAK inhibitors JAK inhibitor AA Rogaine Propecia

TLDR JAK inhibitors like tofacitinib can effectively treat severe alopecia areata.

This case report discusses a 24-year-old female with severe alopecia areata (AA) who showed significant improvement after one month of treatment with the Janus kinase (JAK) inhibitor tofacitinib. Despite previous treatments, including minoxidil, corticosteroids, finasteride, and cryotherapy, the patient experienced rapid progression of AA. The report highlights the high emotional and social burden of AA and suggests that JAK inhibitors, such as tofacitinib, can be effective in difficult-to-control cases. This is the first documented successful use of tofacitinib for AA in Colombia.

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research Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis

185 citations , December 2014 in “Journal of Investigative Dermatology”

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research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition

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research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

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4 / 4 results

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