January 2025 in “Biomaterials Research” This study developed a novel zinc-releasing hydrogel, Zn-Gel, which promoted wound healing by controlling zinc ion release and demonstrated excellent compatibility and efficacy in enhancing cell proliferation, blood vessel formation, and tissue regeneration in vitro and in vivo settings.
November 2024 in “ACS Materials Letters” This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.
April 2024 in “Materials today bio” In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.
October 2022 in “Regenerative Biomaterials” This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
May 2022 in “Research Square (Research Square)” This study found that the newly developed transdermal oil body microgel emulsion (OBEME) improved wound healing in mice by enhancing skin permeability, reducing inflammation, and promoting new blood vessel formation and re-epithelialization.
October 2020 in “Plastic Surgery” This study found that topical transplantation of green fluorescent protein-labeled bone marrow mesenchymal stem cells significantly improved regeneration of deeper wounds, with increased blood vessel formation, compared to control in a rat model.
This study found that topical mesenchymal stem cell conditioned medium improved skin structure by increasing collagen fiber density, hair follicles, and blood vessel number in a mouse model of skin aging.
April 2017 in “Journal of Investigative Dermatology” This study suggests that sirolimus and propranolol may reduce abnormal lymphatic endothelial cell proliferation in lymphatic malformations, potentially improving vessel function and patient outcomes.
Botulinum toxin-A may increase hair growth and reduce hair loss in men with baldness, and injecting near blood vessels can improve pain relief and last longer.
April 2012 in “The FASEB Journal” In this study, researchers observed that knocking down the LPA 4 receptor in zebrafish embryos led to vascular and lymph vessel development abnormalities, including edema and decreased heartbeats.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
January 2010 in “Xiandai yaowu yu linchuang” In this mouse study, Yangxue Shengfa Capsules were associated with promoted hair growth by increasing VEGF levels, hair follicle number, and skin blood vessels.
January 2007 in “Journal of The American Academy of Dermatology” Propylthiouracil, a thyroid medication, can cause skin blood clots and immune-related blood vessel inflammation.
August 2004 in “Journal of the American College of Surgeons” Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
January 2023 in “International Journal of Molecular Sciences” This study found that a double-crosslinked hydrogel using GelMA and sulfhydrylated chitosan showed promising results in healing full-thickness skin wounds in rats by accelerating tissue repair and promoting collagen and blood vessel formation.
November 2022 in “Journal of Nanobiotechnology” In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.
August 2026 in “International Journal of Pharmaceutical and Clinical Research” This review synthesizes knowledge on HTRA1-associated disorders, highlighting how mutations in the HTRA1 gene are linked to cerebral small vessel disease and systemic conditions, and discusses emerging diagnostic and therapeutic strategies aimed at precision medicine.
June 2026 in “International Journal of Drug Delivery Technology” In this study using fertilized chicken eggs, researchers reported that ethanol and aqueous extracts of clove, cinnamon, and coriander significantly reduced blood vessel formation, indicating these herbs' potential as safe anti-angiogenic treatments without severe side effects compared to synthetic drugs.
January 2026 in “Advanced Healthcare Materials” This study developed a 3D-printed scaffold for diabetic wound repair, which showed potential in a mouse model by reducing inflammation, promoting blood vessel regeneration, enhancing skin hydration, and accelerating wound healing through nitric oxide and gallium ion release, oxidative stress modulation, and antioxidant pathway activation.
June 2025 in “Stem Cells and Cloning Advances and Applications” In this study, researchers demonstrated that their technology efficiently produces CFx-δ2 from stem cells and accelerates wound healing by enhancing fibroblast activity, reducing inflammation, and promoting blood vessel formation.
March 2025 in “Journal of Controlled Release” This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.
This study found that in beagles with benign prostate hyperplasia, finasteride treatment increased blood volume and decreased vessel leakiness in the prostate's parenchymal zone as shown by dynamic contrast-enhanced MRI.
123 citations
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January 2012 in “The Keio Journal of Medicine” This review discusses anti-angiogenic therapy for cancer, highlighting VEGF blockers' effectiveness but also their limitations, such as resistance and adverse effects; it reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found an increased number of perivascular mast cells and upregulated CB1 expression in patients with IgA vasculitis compared to healthy individuals, suggesting potential involvement in the disease's pathogenesis and inflammation.
3 citations
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October 2021 in “Turkish Journal Of Neurology” This study identifies novel genetic variants in the NOTCH3 and HTRA1 genes associated with CADASIL and CARASIL, highlighting their potential in supporting clinical diagnosis and informing treatment strategies.
119 citations
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May 1987 in “The Journal of Dermatologic Surgery and Oncology” This study found that pigmentation following sclerotherapy is likely caused by hemosiderin deposition from red blood cells rather than post-inflammatory hyperpigmentation, with most cases resolving spontaneously within 6–24 months.
23 citations
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June 2015 in “Experimental Dermatology” In this study, Mills et al. reported that inoculating human pericytes into murine wounds delayed dermal repair, revealing a need for better understanding of pericyte activity during skin injury repair.
5 citations
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June 2012 in “PubMed” This article discusses leukocytoclastic vasculitis, particularly its triggers, manifestations, and treatments, and reports no new experimental results; the authors highlight valproic acid's association with this condition.
322 citations
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January 1997 in “Thrombosis and Haemostasis” This review discusses factors influencing angiogenesis, focusing on vascular permeability factor as a key inducer and thrombospondin as a notable inhibitor, and recommends exploring molecular mechanisms for therapeutic interventions.
76 citations
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June 2008 in “Journal of the American Academy of Dermatology” In this study, key histologic features such as mucinous perifollicular fibroplasia were identified to aid in the diagnosis of lichen planopilaris.