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RCM and OCT are effective for diagnosing and monitoring hair-related skin diseases but lack standardized protocols and need more research.

Most pregnant women experience skin changes, especially increased pigmentation.

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Reflectance confocal microscopy helped tell periorificial dermatitis apart from similar skin conditions.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Mice with alopecia areata had wider lymphatic vessels in their skin.

Blood vessel patterns in skin diseases relate to certain blood markers in systemic sclerosis but not in psoriasis or psoriatic arthritis, and may indicate circulation issues in alopecia.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.

Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.

The new hair loss treatment combining nitric oxide and minoxidil in a special carrier is effective for hair regrowth.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

High testosterone increases heart disease risk in women with PCOS.

Macrophage iron release is crucial for hair growth and wound healing.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Telocytes in the scalp may help with skin regeneration and maintenance.

Ozone and procaine boost the release of healing factors in platelet-rich plasma.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

Hair growth is cyclic and influenced mainly by local factors.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Telocytes might help with skin repair and regeneration.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.