research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
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research Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient
The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
research A Randomized Pilot Study to Compare Hair Follicle Cell Suspensions Prepared Using Trypsin Alone Versus Trypsin in Combination with Collagenase Type I for Transplantation in Vitiligo
Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.
research Expression of Collagen Type I, Skin Fibroblasts, and Macrophages After 1550 nm Erbium Glass Fractional Laser in Androgenic Alopecia
The 1550 nm fractional Er:Glass laser improved hair regrowth in patients with androgenic alopecia, but didn't significantly change collagen type I, skin fibroblasts, or macrophages. More research is needed for optimal results.
research Topical MK-386, an Inhibitor of 5α-Reductase Type I, Suppresses Sebum DHT
MK-386 reduces sebum DHT levels.
research Rare Case of Leydig Cell Tumor with Type I Diabetes Mellitus Causing Female Pattern Hair Loss
Woman with diabetes had hair loss due to rare ovarian tumor; surgery improved hair growth.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Inhibitors of 5α-Reductase Type I in LNCaP Cells from the Roots of Angelica Koreana
Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.
research Expression Analysis of the Type I Keratin Protein Keratin 33A in Goat Coat Hair
Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
research Plasma-Polymerized Antibacterial Coating of Ovine Tendon Collagen Type I Crosslinked with Genipin and Dehydrothermal-Crosslinked as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Novel Frameshift Mutation in TRPS1 in a Ukrainian Patient with Trichorhinophalangeal Syndrome Type I
A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.
research Scarring Alopecia in Classic Adult Type I Pityriasis Rubra Pilaris
research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
research Changes in Serum Free Testosterone, Sleep Patterns, and 5-Alpha-Reductase Type I Activity Influence Sebum Excretion in Female Subjects
Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.
research Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker
A genetic marker linked to a type of hair loss was found in most patients studied.
research The Efficacy of Ostrich Antibodies to Dihydrotestosterone and 5α-Reductase in the Restoration of Hair Growth
Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.
research Structure of Human Type II 5 Alpha-Reductase Gene
The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
research Insulin Resistance and Obesity Among Infertile Women With Different Polycystic Ovary Syndrome Phenotypes
Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: An Outpatient-Based Study
AGA increased yearly, type I most common, and family history and seborrheic dermatitis often linked.
research Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus
PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.
research Alterations of Collagen Type 1, Skin Fibroblasts, and Macrophages in the Scalp Following the Treatment of 1550-nm Erbium Glass Fractional Laser for Androgenetic Alopecia
Laser treatment shows promise for hair growth, but needs further research.
research Co-Occurrence of Monilethrix and Type 1 Diabetes Mellitus
The girl has both monilethrix and Type 1 diabetes, but no link between the two conditions is known.
research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle
K6hf is a unique protein found only in a specific layer of hair follicles.
research Structure of Human Type II 5 Alpha-Reductase Gene
The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
research Responses of Type II Spiral Ganglion Neurites to Stripes of Laminin and Fibronectin
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
research Effect of Skin Type on Efficacy of Laser Treatment for Androgenetic Alopecia: A Review of the Literature
Laser treatment for hair loss works equally well on different skin types, but more research is needed for very dark skin.
research Dietary Therapy in Type II Diabetes Mellitus
Eating less calories, focusing on complex carbs, and reducing fats can help manage type II diabetes.
research Skin Type and Efficacy of Laser Treatment for Androgenic Alopecia
More research is needed to understand how skin type affects laser treatment for hair loss.
research A Powerful Method for Pleiotropic Analysis Under Composite Null Hypothesis Identifies Novel Shared Loci Between Type 2 Diabetes and Prostate Cancer
New method finds genetic links between Type 2 Diabetes and Prostate Cancer not seen before.