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The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Finasteride doesn't harm bone density in older men with BPH.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

Finasteride treats baldness but may cause lasting sexual side effects.

Sebocytes play a key role in controlling androgen levels in human skin.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Acankoreoside J from Acanthopanax koreanum may help promote hair growth.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.