Androgens and Hair: A Biological Paradox

January 2001 in “ Cambridge University Press eBooks ”

Valerie A. Randall

androgens hair growth androgenetic alopecia hair follicle antiandrogens cyproterone acetate 5α-reductase inhibitors finasteride Propecia

TLDR Androgens can cause hair growth in some areas but hair loss on the scalp.

The document "Androgens and hair: a biological paradox" explored the complex and paradoxical effects of androgens on hair growth, where they stimulate hair growth in certain body areas but inhibit it on the scalp, leading to conditions like androgenetic alopecia. It highlighted the role of androgens in hair follicle function, the genetic predisposition to hair loss, and the psychological impact of these conditions. Treatments such as antiandrogens (cyproterone acetate) and 5α-reductase inhibitors (finasteride) were discussed, though their efficacy varied. The document emphasized the need for continuous treatment and further research to better understand and manage androgen-related hair disorders.

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