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Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Minoxidil and finasteride can slow or halt hair loss, but may have side effects.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Massaging the scalp with a cosmetic containing certain natural inhibitors can significantly regrow hair in men with pattern baldness.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Finasteride blocks progesterone's effect on absence seizures in rats.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.