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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

The study created a new method to test drugs that affect hormone processing in skin.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Gene differences may affect baldness treatment response in Korean men.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Compound 4 is a promising treatment for hair loss with low toxicity.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Rice bran extract might help prevent hair loss.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

A new compound effectively inhibits human 5α-reductase 1.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.